Examining the effects of age and sex on tau PET binding in the absence of beta‐amyloid pathology
Gordon B, Flores S, Dincer A, Keefe S, McKay N, Hobbs D, Wisch J, Hornbeck R, Franklin E, Jack C, Koeppe R, Xiong C, McDade E, van Dyck C, Klein G, Pariente J, Bateman R, Morris J, Perrin R, Benzinger T. Examining the effects of age and sex on tau PET binding in the absence of beta‐amyloid pathology. Alzheimer's & Dementia 2022, 18 DOI: 10.1002/alz.063285.Peer-Reviewed Original ResearchPrimary age-related tauopathyTau-PET bindingTau-PETTemporal gyrusPET bindingBeta-amyloid pathologyAge-related tauopathyRostral middle frontal gyrusSubthreshold levelsElevated tracer uptakeTau PET imagingTau bindingInferior temporal gyrusInferior temporal cortexMiddle frontal gyrusSuperior temporal gyrusEffect of ageAlzheimer pathologyAmyloid pathologySignificant positive associationLateral parietalTemporal cortexTracer uptakeAlzheimer's diseaseSecondary analysis