2017
A novel association between high red blood cell alloimmunization rates and hereditary hemorrhagic telangiectasia
Zheng Y, Pollak J, Henderson K, Hendrickson JE, Tormey CA. A novel association between high red blood cell alloimmunization rates and hereditary hemorrhagic telangiectasia. Transfusion 2017, 58: 775-780. PMID: 29210083, DOI: 10.1111/trf.14451.Peer-Reviewed Original ResearchConceptsHereditary hemorrhagic telangiectasiaRBC alloimmunization rateAlloimmunization rateHHT patientsRBC transfusionHemorrhagic telangiectasiaRed blood cell transfusionProphylactic antigen matchingBlood cell transfusionTertiary care facilityMultiple arteriovenous malformationsAutosomal dominant disorderCommon alloantibodiesHHT populationCell transfusionSurgical bleedingTransfusion burdenAntigen matchingSpontaneous hemorrhageRetrospective studyMedical recordsArteriovenous malformationsCare facilitiesPatientsDisease pathophysiologyIrradiation of Red Blood Cells and Alloimmunization
Tormey CA, Hendrickson JE. Irradiation of Red Blood Cells and Alloimmunization. Lab Medicine 2017, 48: 172-177. PMID: 28340248, DOI: 10.1093/labmed/lmx018.Peer-Reviewed Original ResearchConceptsAlloimmunization rateRBC alloimmunization rateTime of transfusionRBC unit transfusionPostoperative bleedingRed blood cell damageRed blood cellsRBC transfusionCommon diagnosisImmunosuppressive disordersTransfusion recipientsBlood cell damageAnimal modelsStudy subjectsTransfusionControl groupRBC antigensAntibody screeningRBC unitsPatientsBlood cellsCell damageRBCsOxidative damageDiagnosis
2016
Red Blood Cell Antibodies in Hematology/Oncology Patients Interpretation of Immunohematologic Tests and Clinical Significance of Detected Antibodies
Hendrickson JE, Tormey CA. Red Blood Cell Antibodies in Hematology/Oncology Patients Interpretation of Immunohematologic Tests and Clinical Significance of Detected Antibodies. Hematology/Oncology Clinics Of North America 2016, 30: 635-651. PMID: 27113001, DOI: 10.1016/j.hoc.2016.01.006.Peer-Reviewed Original ResearchConceptsRed blood cell transfusionRed blood cell antibodiesRBC alloimmunization rateBlood cell transfusionManagement of patientsDevelopment of alloantibodiesBlood group antigensAlloimmunization rateRBC alloimmunizationSuch alloantibodiesCell transfusionCell antibodiesClinical significanceHemolytic anemiaPatients' interpretationsDetected antibodiesTransfusionGroup antigensBlood bankCompatible unitsAntibodiesAlloantibodiesOncology disordersDeleterious consequencesAlloimmunization
2014
Red Blood Cell Alloimmunization Mitigation Strategies
Hendrickson JE, Tormey CA, Shaz BH. Red Blood Cell Alloimmunization Mitigation Strategies. Transfusion Medicine Reviews 2014, 28: 137-144. PMID: 24928468, DOI: 10.1016/j.tmrv.2014.04.008.Peer-Reviewed Original ResearchConceptsHemolytic transfusion reactionsRBC alloantibodiesRBC alloimmunizationTransfusion reactionsImmune systemRed blood cell alloantibodiesCompatible RBC unitsRBC alloimmunization rateTransfusion-associated morbidityRecipient's immune systemTransfusion-associated deathForms of anemiaAlloimmunization rateAntigen exposureSignificant morbidityTransfusion recipientsHemolytic diseaseAlloantibodiesHuman studiesAnimal studiesDanger signalsAnimal dataMorbidityAlloimmunizationRBC units