2023
The use of continuous positive airway pressure in COPD-OSA overlap syndrome: A systematic review
Srivali N, Thongprayoon C, Tangpanithandee S, Cheungpasitporn W, Won C. The use of continuous positive airway pressure in COPD-OSA overlap syndrome: A systematic review. Sleep Medicine 2023, 108: 55-60. PMID: 37336060, DOI: 10.1016/j.sleep.2023.05.025.Peer-Reviewed Original ResearchMeSH KeywordsContinuous Positive Airway PressureHumansPulmonary Disease, Chronic ObstructiveSleep Apnea, ObstructiveConceptsChronic obstructive pulmonary diseaseObstructive sleep apneaDefinition of COPDCPAP therapyOverlap syndromeSystematic reviewCOPD exacerbationsCPAP usageClinical outcomesContinuous positive airway pressure therapyPositive airway pressure therapyContinuous positive airway pressureNewcastle-Ottawa Quality ScaleAirway pressure therapyPositive airway pressureObstructive pulmonary diseaseMeta-Analyses (PRISMA) statementPreferred Reporting ItemsComprehensive systematic reviewAirway pressurePulmonary diseaseSleep apneaPressure therapyPatient populationReporting ItemsInternational Consensus Statement on Obstructive Sleep Apnea
Chang JL, Goldberg AN, Alt JA, Mohammed A, Ashbrook L, Auckley D, Ayappa I, Bakhtiar H, Barrera J, Bartley B, Billings M, Boon M, Bosschieter P, Braverman I, Brodie K, Cabrera‐Muffly C, Caesar R, Cahali M, Cai Y, Cao M, Capasso R, Caples S, Chahine L, Chang C, Chang K, Chaudhary N, Cheong C, Chowdhuri S, Cistulli P, Claman D, Collen J, Coughlin K, Creamer J, Davis E, Dupuy‐McCauley K, Durr M, Dutt M, Ali M, Elkassabany N, Epstein L, Fiala J, Freedman N, Gill K, Gillespie M, Golisch L, Gooneratne N, Gottlieb D, Green K, Gulati A, Gurubhagavatula I, Hayward N, Hoff P, Hoffmann O, Holfinger S, Hsia J, Huntley C, Huoh K, Huyett P, Inala S, Ishman S, Jella T, Jobanputra A, Johnson A, Junna M, Kado J, Kaffenberger T, Kapur V, Kezirian E, Khan M, Kirsch D, Kominsky A, Kryger M, Krystal A, Kushida C, Kuzniar T, Lam D, Lettieri C, Lim D, Lin H, Liu S, MacKay S, Magalang U, Malhotra A, Mansukhani M, Maurer J, May A, Mitchell R, Mokhlesi B, Mullins A, Nada E, Naik S, Nokes B, Olson M, Pack A, Pang E, Pang K, Patil S, Van de Perck E, Piccirillo J, Pien G, Piper A, Plawecki A, Quigg M, Ravesloot M, Redline S, Rotenberg B, Ryden A, Sarmiento K, Sbeih F, Schell A, Schmickl C, Schotland H, Schwab R, Seo J, Shah N, Shelgikar A, Shochat I, Soose R, Steele T, Stephens E, Stepnowsky C, Strohl K, Sutherland K, Suurna M, Thaler E, Thapa S, Vanderveken O, de Vries N, Weaver E, Weir I, Wolfe L, Woodson B, Won C, Xu J, Yalamanchi P, Yaremchuk K, Yeghiazarians Y, Yu J, Zeidler M, Rosen I. International Consensus Statement on Obstructive Sleep Apnea. International Forum Of Allergy & Rhinology 2023, 13: 1061-1482. PMID: 36068685, PMCID: PMC10359192, DOI: 10.1002/alr.23079.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAdultContinuous Positive Airway PressureHumansPolysomnographyRisk FactorsSleep Apnea, ObstructiveConceptsObstructive sleep apneaEvidence-based reviewPositive airway pressureInternational consensus statementSleep apneaConsensus statementAdult OSA patientsMultiple treatment modalitiesSleep apnea evaluationAirway pressureOSA patientsPAP adherenceSurgical treatmentEvidence-based practiceOSA treatmentLongitudinal careTreatment modalitiesClinical managementRisk factorsHealth risk outcomesStudy qualitySyndrome definitionCurrent evidenceRecommendation formatOSA disease
2019
Sex differences in obstructive sleep apnea phenotypes, the multi-ethnic study of atherosclerosis
Won C, Reid M, Sofer T, Azarbarzin A, Purcell S, White D, Wellman A, Sands S, Redline S. Sex differences in obstructive sleep apnea phenotypes, the multi-ethnic study of atherosclerosis. Sleep 2019, 43: zsz274. PMID: 31687772, PMCID: PMC7215264, DOI: 10.1093/sleep/zsz274.Peer-Reviewed Original ResearchMeSH KeywordsAtherosclerosisFemaleHumansMalePhenotypeRetrospective StudiesSex CharacteristicsSleep Apnea, ObstructiveSleep, REMConceptsApnea-hypopnea indexObstructive sleep apneaMulti-Ethnic StudyArousal criteriaObstructive sleep apnea phenotypesSex differencesLow arousal thresholdRelative sex differencesApnea phenotypesNREM-AHIPathophysiological endotypesREM-OSAAirway collapsibilityOSA prevalenceSleep apneaDesaturation criteriaEndotypesSex disparitiesArousal thresholdPolysomnography dataSignificant sex differencesREM eventsWomenLow loop gainNREM
2018
Varying Hypopnea Definitions Affect Obstructive Sleep Apnea Severity Classification and Association With Cardiovascular Disease.
Won CHJ, Qin L, Selim B, Yaggi HK. Varying Hypopnea Definitions Affect Obstructive Sleep Apnea Severity Classification and Association With Cardiovascular Disease. Journal Of Clinical Sleep Medicine 2018, 14: 1987-1994. PMID: 30518445, PMCID: PMC6287733, DOI: 10.5664/jcsm.7520.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaHypopnea definitionsDesaturation criteriaOdds ratioCardiovascular diseaseOSA diagnosisSeverity of OSAModerate obstructive sleep apneaSevere obstructive sleep apneaDifferent hypopnea definitionsLess smoking historySleep-disordered breathingIschemic heart diseaseSignificant risk factorsCross-sectional analysisArousal definitionHypopnea criteriaCardiovascular riskOSA severitySmoking historyHeart failureClinical featuresSleep apneaOSA groupRisk factorsDiagnosing and Treating Sleep Apnea in Patients With Acute Cerebrovascular Disease
Bravata DM, Sico J, Fragoso C, Miech EJ, Matthias MS, Lampert R, Williams LS, Concato J, Ivan CS, Fleck JD, Tobias L, Austin C, Ferguson J, Radulescu R, Iannone L, Ofner S, Taylor S, Qin L, Won C, Yaggi HK. Diagnosing and Treating Sleep Apnea in Patients With Acute Cerebrovascular Disease. Journal Of The American Heart Association 2018, 7: e008841. PMID: 30369321, PMCID: PMC6201384, DOI: 10.1161/jaha.118.008841.Peer-Reviewed Original ResearchConceptsContinuous positive airway pressure usePositive airway pressure useTransient ischemic attackRankin Scale scoreIschemic stroke/transient ischemic attackStroke/transient ischemic attackBackground Obstructive sleep apneaHealth Stroke ScaleIschemic attackScale scoreStroke ScaleIschemic strokeTreat analysisSleep apneaAcute ischemic stroke/transient ischemic attackHealth Stroke Scale scoreNational InstituteContinuous positive airway pressureModified Rankin Scale scoreNeurological functioningNeurological symptom severityRecent ischemic strokeStroke Scale scoreAcute cerebrovascular diseaseAcute ischemic stroke
2017
Man Versus Machine.
Won CH. Man Versus Machine. Journal Of Clinical Sleep Medicine 2017, 13: 167-168. PMID: 28095981, PMCID: PMC5263070, DOI: 10.5664/jcsm.6436.Commentaries, Editorials and LettersHumansSleep Apnea, Obstructive
2015
The Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study: design, rationale, and methods
Koo BB, Won C, Selim BJ, Qin L, Jeon S, Redeker NS, Bravata DM, Strohl KP, Concato J, Zinchuk AV, Yaggi HK. The Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study: design, rationale, and methods. Sleep And Breathing 2015, 20: 893-900. PMID: 26642771, DOI: 10.1007/s11325-015-1254-3.Peer-Reviewed Original ResearchConceptsCardiovascular outcomesVascular eventsSleep architecturePrognostic modelRetrospective observational cohort studyMain primary outcomeMiddle-aged veteransTransient ischemic attackAcute coronary syndromeObservational cohort studyResultsThe study populationCongestive heart failureSleep-disordered breathingVA Patient Treatment FileVital Status filesPatient Treatment FileComputerized patient record systemVeterans Affairs centersPost-traumatic stress disorderIschemic attackCoronary syndromeCohort studySecondary outcomesComposite endpointGlycemic control
2012
Severe obstructive sleep apnea increases mortality in patients with ischemic heart disease and myocardial injury
Won CH, Chun HJ, Chandra SM, Sarinas PS, Chitkara RK, Heidenreich PA. Severe obstructive sleep apnea increases mortality in patients with ischemic heart disease and myocardial injury. Sleep And Breathing 2012, 17: 85-91. PMID: 22294346, DOI: 10.1007/s11325-012-0653-y.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngina, UnstableBody Mass IndexCause of DeathCohort StudiesComorbidityContinuous Positive Airway PressureEchocardiographyFemaleFollow-Up StudiesHeart FailureHumansKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionMyocardial IschemiaPatient CompliancePolysomnographyPrognosisRiskRisk FactorsSleep Apnea, ObstructiveSurvival AnalysisTroponin IConceptsSevere obstructive sleep apneaObstructive sleep apneaIschemic heart diseaseSleep apneaMyocardial injuryHeart diseaseOSA groupMild-moderate obstructive sleep apneaModerate obstructive sleep apneaPrevious myocardial injuryAdjusted hazard ratioRetrospective cohort studyConsecutive OSA patientsElevated troponin levelsSevere OSA groupRisk of deathDose-dependent impactCohort studyHazard ratioOSA patientsOSA severityTroponin levelsConclusionsThe severityRisk stratificationCardiac patients
2008
Surgical Treatment of Obstructive Sleep Apnea
Won CH, Li KK, Guilleminault C. Surgical Treatment of Obstructive Sleep Apnea. Annals Of The American Thoracic Society 2008, 5: 193-199. PMID: 18250212, DOI: 10.1513/pats.200708-121mg.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsClinical CompetenceHumansLarynxMandibleMaxillaNosePatient SelectionPharynxPostoperative ComplicationsSleep Apnea, ObstructiveConceptsObstructive sleep apneaPositive airway pressure therapySevere obstructive sleep apneaAirway pressure therapyRadiofrequency ablationMaxillomandibular advancementSleep apneaPressure therapyMaxillomandibular deficiencyUpper airway surgeryUpper airway obstructionImportant treatment optionLaser-assisted uvulopalatoplastyProper patient selectionImportant therapeutic considerationProper procedure selectionGenioglossal advancementRetrolingual obstructionUvulopalatal flapAirway obstructionNasal obstructionSurgical treatmentAirway surgeryPatient selectionMost surgeries