2018
Varying Hypopnea Definitions Affect Obstructive Sleep Apnea Severity Classification and Association With Cardiovascular Disease.
Won CHJ, Qin L, Selim B, Yaggi HK. Varying Hypopnea Definitions Affect Obstructive Sleep Apnea Severity Classification and Association With Cardiovascular Disease. Journal Of Clinical Sleep Medicine 2018, 14: 1987-1994. PMID: 30518445, PMCID: PMC6287733, DOI: 10.5664/jcsm.7520.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaHypopnea definitionsDesaturation criteriaOdds ratioCardiovascular diseaseOSA diagnosisSeverity of OSAModerate obstructive sleep apneaSevere obstructive sleep apneaDifferent hypopnea definitionsLess smoking historySleep-disordered breathingIschemic heart diseaseSignificant risk factorsCross-sectional analysisArousal definitionHypopnea criteriaCardiovascular riskOSA severitySmoking historyHeart failureClinical featuresSleep apneaOSA groupRisk factors
2012
Severe obstructive sleep apnea increases mortality in patients with ischemic heart disease and myocardial injury
Won CH, Chun HJ, Chandra SM, Sarinas PS, Chitkara RK, Heidenreich PA. Severe obstructive sleep apnea increases mortality in patients with ischemic heart disease and myocardial injury. Sleep And Breathing 2012, 17: 85-91. PMID: 22294346, DOI: 10.1007/s11325-012-0653-y.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngina, UnstableBody Mass IndexCause of DeathCohort StudiesComorbidityContinuous Positive Airway PressureEchocardiographyFemaleFollow-Up StudiesHeart FailureHumansKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionMyocardial IschemiaPatient CompliancePolysomnographyPrognosisRiskRisk FactorsSleep Apnea, ObstructiveSurvival AnalysisTroponin IConceptsSevere obstructive sleep apneaObstructive sleep apneaIschemic heart diseaseSleep apneaMyocardial injuryHeart diseaseOSA groupMild-moderate obstructive sleep apneaModerate obstructive sleep apneaPrevious myocardial injuryAdjusted hazard ratioRetrospective cohort studyConsecutive OSA patientsElevated troponin levelsSevere OSA groupRisk of deathDose-dependent impactCohort studyHazard ratioOSA patientsOSA severityTroponin levelsConclusionsThe severityRisk stratificationCardiac patients
2008
Surgical Treatment of Obstructive Sleep Apnea
Won CH, Li KK, Guilleminault C. Surgical Treatment of Obstructive Sleep Apnea. Annals Of The American Thoracic Society 2008, 5: 193-199. PMID: 18250212, DOI: 10.1513/pats.200708-121mg.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsObstructive sleep apneaPositive airway pressure therapySevere obstructive sleep apneaAirway pressure therapyRadiofrequency ablationMaxillomandibular advancementSleep apneaPressure therapyMaxillomandibular deficiencyUpper airway surgeryUpper airway obstructionImportant treatment optionLaser-assisted uvulopalatoplastyProper patient selectionImportant therapeutic considerationProper procedure selectionGenioglossal advancementRetrolingual obstructionUvulopalatal flapAirway obstructionNasal obstructionSurgical treatmentAirway surgeryPatient selectionMost surgeries