2022
Retinal vein occlusion is associated with stroke independent of underlying cardiovascular disease
Bakhoum C, Madala S, Long C, Adabifirouzjaei F, Freeman W, Goldbaum M, DeMaria A, Bakhoum M. Retinal vein occlusion is associated with stroke independent of underlying cardiovascular disease. Eye 2022, 37: 764-767. PMID: 35411111, PMCID: PMC9998396, DOI: 10.1038/s41433-022-02038-x.Peer-Reviewed Original ResearchConceptsRetinal vein occlusionPresence of RVORisk of strokeCardiovascular diseaseOdds ratioVein occlusionRisk factorsMultivariable logistic regression modelCoronary artery diseaseCross-sectional studyYears of ageLogistic regression modelsArtery diseaseDiabetes mellitusCarotid diseaseStroke developmentAtrial fibrillationLeading causeYoung subjectsEarly interventionStrokeOlder individualsConclusionsOur findingsDiseaseRiskActivated phosphoinositide 3-kinase δ syndrome associated with nephromegaly, growth hormone deficiency, bronchiectasis: a case report
Craig M, Geng B, Wigby K, Phillips S, Bakhoum C, Naheedy J, Cernelc-Kohan M. Activated phosphoinositide 3-kinase δ syndrome associated with nephromegaly, growth hormone deficiency, bronchiectasis: a case report. Allergy, Asthma & Clinical Immunology 2022, 18: 15. PMID: 35189965, PMCID: PMC8862239, DOI: 10.1186/s13223-022-00655-5.Peer-Reviewed Original ResearchGrowth hormone deficiencyHormone deficiencyPI3K pathwayAnatomic abnormalitiesUnique presentationOligoarticular juvenile idiopathic arthritisCase presentationThe patientK pathwayPatient's unique presentationJuvenile idiopathic arthritisUnique clinical featuresNine-year-old boyYears of ageMild developmental delayWhole-exome sequencingMultidisciplinary collaborative approachImmune cytopeniasHip painMicroscopic hematuriaRecurrent sinusitisBilateral nephromegalyGH therapyIdiopathic arthritisClinical featuresUnclear etiology
2021
Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort
Chan AX, Bakhoum CY, Bangen KJ, Bakhoum MF. Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort. American Journal Of Ophthalmology 2021, 226: 201-205. PMID: 33529587, PMCID: PMC9227960, DOI: 10.1016/j.ajo.2021.01.026.Peer-Reviewed Original ResearchConceptsRetinal vascular occlusionVascular occlusionCognitive dementiaHigh prevalenceMultiple logistic regression analysisCross-sectional studyLogistic regression analysisYears of ageElectronic medical recordsMedical visitsMedical recordsRisk factorsDiagnostic codesStudy populationInternational ClassificationSectional cohortSignificant associationDementiaOlder ageOcclusionStrokeAgeRegression analysisPrevalenceAssociation