2023
Association of clinical characteristics with urine uromodulin in children with chronic kidney disease
Faulkner S, Matheson M, Greenberg J, Garimella P, Furth S, Ix J, Bakhoum C. Association of clinical characteristics with urine uromodulin in children with chronic kidney disease. Pediatric Nephrology 2023, 38: 3859-3862. PMID: 36988691, PMCID: PMC10528151, DOI: 10.1007/s00467-023-05947-5.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseUrine uromodulinUromodulin levelsGlomerular diseaseKidney diseaseEtiology of CKDGraphical abstractA higher resolution versionOlder ageMultivariable linear regressionAge-specific referenceGreater kidney sizeHigh urine concentrationsRelationship of ageConclusionsAmong childrenTubular healthClinical characteristicsMedian eGFRMedian agePrimary outcomeKidney functionKidney sizeMultivariable modelChild CohortUrine concentrationsHealthy adults
2022
Urine Uromodulin Is Not Associated With Blood Pressure in the Chronic Kidney Disease in Children Cohort
Bakhoum CY, Matheson MB, Greenberg JH, Furth SL, Ix JH, Garimella PS. Urine Uromodulin Is Not Associated With Blood Pressure in the Chronic Kidney Disease in Children Cohort. Hypertension 2022, 79: 2298-2304. PMID: 35920156, PMCID: PMC9458625, DOI: 10.1161/hypertensionaha.122.19566.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseClinic blood pressureSystolic blood pressureBlood pressureUromodulin levelsKidney diseaseChild CohortMean systolicSodium intakeClinic systolic blood pressureMean systolic blood pressureHealthy pediatric cohortDiastolic blood pressureGlomerular filtration rateHigh blood pressureMultivariable linear regression modelsLoop of HenleUrine uromodulinDietary sodiumMedian ageSalt intakePediatric cohortFiltration rateGlomerular diseaseMultivariable model