2023
Does This Child With High Blood Pressure Have Secondary Hypertension?
Nugent J, Jiang K, Funaro M, Saran I, Young C, Ghazi L, Bakhoum C, Wilson F, Greenberg J. Does This Child With High Blood Pressure Have Secondary Hypertension? JAMA 2023, 329: 1012-1021. PMID: 36976276, DOI: 10.1001/jama.2023.3184.Peer-Reviewed Original ResearchConceptsBlood pressure loadAmbulatory blood pressure monitoringSecondary hypertensionBlood pressure monitoringPrimary hypertensionFamily historyBlood pressurePressure monitoringDiastolic blood pressure loadSystolic blood pressure loadSerum uric acid concentrationAmbulatory blood pressureHigh blood pressureHistory of prematurityPrimary care clinicsRisk of biasNumber of patientsDatabases of MEDLINEDiagnostic Accuracy Studies toolLower body weightRandom-effects modelingUric acid concentrationWeb of ScienceLikelihood ratioAsymptomatic presentation
2021
Proteinuria and nocturnal blood pressure dipping in hypertensive children and adolescents
Bakhoum CY, Vuong KT, Carter CE, Gabbai FB, Ix JH, Garimella PS. Proteinuria and nocturnal blood pressure dipping in hypertensive children and adolescents. Pediatric Research 2021, 90: 876-881. PMID: 33504962, PMCID: PMC8313642, DOI: 10.1038/s41390-020-01315-3.Peer-Reviewed Original ResearchConceptsAmbulatory blood pressure monitoringBody mass indexAssociation of proteinuriaBlood pressureRisk factorsUrine PCRNocturnal blood pressure dippingKidney function declineNocturnal blood pressureAdverse cardiovascular outcomesElevated blood pressureModifiable risk factorsDiastolic blood pressureGlomerular filtration rateBlood pressure dippingBlood pressure monitoringSpot urine proteinHypertensive childrenImpactOur studyCardiovascular outcomesCreatinine ratioFunction declineMass indexProspective studyUrine protein