2015
Independent evaluation of a simple clinical prediction rule to identify right ventricular dysfunction in patients with shortness of breath
Russell FM, Moore CL, Courtney DM, Kabrhel C, Smithline HA, Nordenholz KE, Richman PB, O'Neil BJ, Plewa MC, Beam DM, Mastouri R, Kline JA. Independent evaluation of a simple clinical prediction rule to identify right ventricular dysfunction in patients with shortness of breath. The American Journal Of Emergency Medicine 2015, 33: 542-547. PMID: 25769797, PMCID: PMC7032017, DOI: 10.1016/j.ajem.2015.01.026.Peer-Reviewed Original ResearchConceptsRight ventricular dysfunctionClinical decision ruleSimple clinical prediction ruleRV dysfunctionPersistent dyspneaClinical prediction ruleVentricular dysfunctionDyspneic emergency department (ED) patientsProspective observational multicenter studyPrediction ruleIsolated RV dysfunctionUnexplained persistent dyspneaObservational multicenter studySevere tricuspid regurgitationShortness of breathEmergency department patientsNormal CTPARV hypokinesisStandard careTreatable causeTricuspid regurgitationDepartment patientsMulticenter studyEmergency departmentSame complaint
2009
Potential Impact of Adjusting the Threshold of the Quantitative D‐dimer Based on Pretest Probability of Acute Pulmonary Embolism
Kabrhel C, Courtney D, Camargo CA, Moore CL, Richman PB, Plewa MC, Nordenholtz KE, Smithline HA, Beam DM, Brown MD, Kline JA. Potential Impact of Adjusting the Threshold of the Quantitative D‐dimer Based on Pretest Probability of Acute Pulmonary Embolism. Academic Emergency Medicine 2009, 16: 325-332. PMID: 19298619, DOI: 10.1111/j.1553-2712.2009.00368.x.Peer-Reviewed Original ResearchConceptsNegative predictive valuePulmonary embolismD-dimer testingQuantitative D-dimerPretest probabilityD-dimerVenous thromboembolismQuantitative D-dimer testingPossible pulmonary embolismAcute pulmonary embolismObservational multicenter studyMajority of patientsEmergency department patientsIntermediate pretest probabilityEmergency medicine cliniciansD-dimer cutoffHigh pretest probabilityDifferent D-dimer assaysD-dimer assayEligible patientsDepartment patientsMulticenter studyMedicine cliniciansUnstructured estimatePatients