Migraine—Not Just a Numbers Game
Kopel D, Gottschalk C. Migraine—Not Just a Numbers Game. Neurology 2022, 100: 357-358. PMID: 36396450, DOI: 10.1212/wnl.0000000000201566.Peer-Reviewed Original ResearchConceptsPatient-reported outcome measuresSide effectsAbortive medication useMigraine-related qualityQuality of lifePrimary endpointPreventive therapyMedication useHeadache daysMigraine treatmentPatient populationTreatment optionsPreventive treatmentRecent trialsMigraine pathophysiologyNeurologic disordersDrug trialsOutcome measuresPatient confidenceMost headachesPrescription choicesClinical practicePatientsTherapyMore yearsThe importance of an early onset of migraine prevention: an evidence-based, hypothesis-driven scoping literature review
Gottschalk C, Buse DC, Marmura MJ, Torphy B, Pavlovic JM, Dumas PK, Lalvani N, Blumenfeld A. The importance of an early onset of migraine prevention: an evidence-based, hypothesis-driven scoping literature review. Therapeutic Advances In Neurological Disorders 2022, 15: 17562864221095902. PMID: 35662957, PMCID: PMC9160905, DOI: 10.1177/17562864221095902.Peer-Reviewed Original ResearchMigraine preventionEarly onsetDay 1Migraine daysAvailable clinical trial evidenceAnti-CGRP monoclonal antibodiesFirst treatment weekMigraine preventive therapyMigraine preventive treatmentTraditional oral agentsWeekly migraine daysClinical trial evidenceLeast moderate severityPatient-level outcomesRelevant benefitsOnset preventionOral agentsPreventive therapyChronic migraineMigraine frequencyTrial evidenceTreatment weekPreventive treatmentModerate severityPreventive benefits