2016
YKL-40 Associates with Renal Recovery in Deceased Donor Kidney Transplantation
Puthumana J, Hall IE, Reese PP, Schröppel B, Weng FL, Thiessen-Philbrook H, Doshi MD, Rao V, Lee CG, Elias JA, Cantley LG, Parikh CR. YKL-40 Associates with Renal Recovery in Deceased Donor Kidney Transplantation. Journal Of The American Society Of Nephrology 2016, 28: 661-670. PMID: 27451287, PMCID: PMC5280016, DOI: 10.1681/asn.2016010091.Peer-Reviewed Original ResearchConceptsYKL-40 concentrationsDonor kidneysYKL-40Renal recoveryDeceased donor kidney transplantationRisk of DGFAcute tubular necrosisDeceased kidney donorsDonor kidney transplantationProspective cohort studyPoor transplant outcomesDeceased donor kidneysOrgan procurement organizationsDonor biomarkersGraft functionKidney transplantationCohort studyGraft failureTransplant outcomesTubular injuryTubular necrosisRecipient outcomesKidney donorsProcurement biopsiesPrognostic biomarker
2015
Associations between Deceased-Donor Urine Injury Biomarkers and Kidney Transplant Outcomes
Reese PP, Hall IE, Weng FL, Schröppel B, Doshi MD, Hasz RD, Thiessen-Philbrook H, Ficek J, Rao V, Murray P, Lin H, Parikh CR. Associations between Deceased-Donor Urine Injury Biomarkers and Kidney Transplant Outcomes. Journal Of The American Society Of Nephrology 2015, 27: 1534-1543. PMID: 26374609, PMCID: PMC4849827, DOI: 10.1681/asn.2015040345.Peer-Reviewed Original ResearchConceptsDelayed graft functionRecipient delayed graft functionKidney injury molecule-1Graft functionInjury biomarkersDonor AKIDeceased donor organ qualityLiver-type fatty acidEarly allograft functionL-FABP concentrationRecipient renal functionUrinary NGAL concentrationsKidney transplant recipientsInjury molecule-1Kidney transplant outcomesAllograft functionUrinary NGALKidney injuryTransplant outcomesTransplant recipientsNGAL concentrationsRenal functionNeutrophil gelatinaseDeceased donorsIL-18