2023
Multicenter retrospective evaluation of magnetic resonance imaging in pediatric and congenital heart disease patients with cardiac implantable electronic devices
Gakenheimer-Smith L, Ou Z, Kuang J, Moore J, Burrows A, Kovach J, Dechert B, Beach C, Ayers M, Tan R, Mostafavifar M, Mah D, Conner T, Turpin S, Avasarala K, Shah M, Webster G, Posey J, Etheridge S, Binka E, Niu M, Asaki S, Lambert L, Pilcher T. Multicenter retrospective evaluation of magnetic resonance imaging in pediatric and congenital heart disease patients with cardiac implantable electronic devices. Heart Rhythm 2023, 20: 1752-1758. PMID: 37648183, DOI: 10.1016/j.hrthm.2023.08.034.Peer-Reviewed Original ResearchConceptsCardiac implantable electronic devicesMagnetic resonance imagingCongenital heart disease patientsHeart disease patientsCHD patientsImplantable electronic devicesDisease patientsMRI scansConditional cardiac implantable electronic devicesMulticenter retrospective evaluationMulticenter retrospective reviewPatient adverse eventsCongenital Cardiac CentreRoutine MRI scansPost-MRIAdverse eventsCardiac centerPrimary outcomeRetrospective reviewMinor symptomsEpicardial leadsRetrospective evaluationPatientsGuideline acceptanceResonance imagingClinical presentation of calmodulin mutations: the International Calmodulinopathy Registry
Crotti L, Spazzolini C, Nyegaard M, Overgaard M, Kotta M, Dagradi F, Sala L, Aiba T, Ayers M, Baban A, Barc J, Beach C, Behr E, Bos J, Cerrone M, Covi P, Cuneo B, Denjoy I, Donner B, Elbert A, Eliasson H, Etheridge S, Fukuyama M, Girolami F, Hamilton R, Horie M, Iascone M, Jiménez-Jaimez J, Jensen H, Kannankeril P, Kaski J, Makita N, Muñoz-Esparza C, Odland H, Ohno S, Papagiannis J, Porretta A, Prandstetter C, Probst V, Robyns T, Rosenthal E, Rosés-Noguer F, Sekarski N, Singh A, Spentzou G, Stute F, Tfelt-Hansen J, Till J, Tobert K, Vinocur J, Webster G, Wilde A, Wolf C, Ackerman M, Schwartz P. Clinical presentation of calmodulin mutations: the International Calmodulinopathy Registry. European Heart Journal 2023, 44: 3357-3370. PMID: 37528649, PMCID: PMC10499544, DOI: 10.1093/eurheartj/ehad418.Peer-Reviewed Original ResearchConceptsClinical presentationPrimary neurological manifestationsCardiac structural abnormalitiesLife-threatening arrhythmia syndromesArrhythmic event rateAbsence of symptomsLife-threatening arrhythmiasSodium channel blockersCongenital heart defectsAntiadrenergic interventionsCardiac eventsHeart failureNeurological manifestationsUnderlying molecular mechanismsDefinitive recommendationsClinical severityChannel blockersObservational studySudden deathIndex caseArrhythmia syndromesHeart defectsPrevalent phenotypeStructural abnormalitiesCurrent managementThe Evolving Role of Insertable Cardiac Monitors in Patients with Congenital Heart Disease
Beach C, Richardson C, Paul T. The Evolving Role of Insertable Cardiac Monitors in Patients with Congenital Heart Disease. Cardiac Electrophysiology Clinics 2023, 15: 413-420. PMID: 37865515, DOI: 10.1016/j.ccep.2023.06.001.Peer-Reviewed Original ResearchConceptsInsertable cardiac monitorCongenital heart diseaseHeart diseaseDiagnostic yieldCardiac monitorHigh arrhythmia riskSymptom-rhythm correlationPatient-specific factorsGenetic arrhythmia syndromesGood diagnostic yieldArrhythmogenic syncopePediatric patientsArrhythmia riskArrhythmia syndromesPatientsDiseaseImplantation techniqueLower ratesEvolving roleRiskComplicationsSyncopeSyndrome
2022
Natural history of TANGO2 deficiency disorder: Baseline assessment of 73 patients
Miyake C, Lay E, Soler-Alfonso C, Glinton K, Houck K, Tosur M, Moran N, Stephens S, Scaglia F, Howard T, Kim J, Pham T, Valdes S, Li N, Murali C, Zhang L, Kava M, Yim D, Beach C, Webster G, Liberman L, Janson C, Kannankeril P, Baxter S, Singer-Berk M, Wood J, Mackenzie S, Sacher M, Ghaloul-Gonzalez L, Pedroza C, Morris S, Ehsan S, Azamian M, Lalani S. Natural history of TANGO2 deficiency disorder: Baseline assessment of 73 patients. Genetics In Medicine 2022, 25: 100352. PMID: 36473599, PMCID: PMC10306319, DOI: 10.1016/j.gim.2022.11.020.Peer-Reviewed Original ResearchConceptsMetabolic crisisNatural historyCardiac crisisDeficiency disordersOngoing natural history studyMedical record reviewNatural history studiesAutosomal recessive diseaseMedian ageMultivitamin supplementationRecord reviewIntermittent ataxiaNeurodevelopmental delayEarly infancyPatientsBaseline assessmentSpeech difficultiesB complexDevelopmental milestonesRecessive diseaseParent interviewsUnrelated familiesAtaxiaHistory studiesProgressive delayLife-threatening cardiac arrhythmia and sudden death during electronic gaming: An international case series and systematic review
Lawley C, Tester M, Sanatani S, Prendiville T, Beach C, Vinocur J, Horie M, Uhm J, Khongphatthanayothin A, Ayers M, Starling L, Yoshida Y, Shah M, Skinner J, Turner C. Life-threatening cardiac arrhythmia and sudden death during electronic gaming: An international case series and systematic review. Heart Rhythm 2022, 19: 1826-1833. PMID: 37850595, DOI: 10.1016/j.hrthm.2022.08.003.Peer-Reviewed Original ResearchConceptsInternational case seriesLife-threatening cardiac arrhythmiasCardiac arrhythmiasCase seriesSystematic reviewCatecholaminergic polymorphic ventricular tachycardiaPolymorphic ventricular tachycardiaLong QT syndromeLethal cardiac arrhythmiasCardiac eventsCoronary ischemiaCardiac surgeryVentricular arrhythmiasCardiac arrestSusceptible childrenVentricular tachycardiaVentricular fibrillationSudden deathCardiac conditionsArrhythmic triggersCardiac diagnosisPatientsQT syndromeSusceptible individualsArrhythmiasCoronavirus disease 2019 and the young heart: prevention, treatment, and return to play
Beach CM, Faherty E, Pesce M. Coronavirus disease 2019 and the young heart: prevention, treatment, and return to play. Current Opinion In Pediatrics 2022, 34: 471-475. PMID: 36036422, PMCID: PMC9593324, DOI: 10.1097/mop.0000000000001167.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCOVID-19 vaccinationRisk factorsSevere diseasePhysical activitySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmissionAcute COVID-19 infectionAcute COVID-19Regular physical activityViral prevalenceCOVID-19 infectionSpecific risk factorsCoronavirus disease 2019Current care modelsPrevention of diseaseInflammatory syndromeCardiac manifestationsPoor outcomeDisease 2019Care modelYoung heartsViral transmissionInfectionDiseaseCOVID-19VaccinationCardiac crises: Cardiac arrhythmias and cardiomyopathy during TANGO2 deficiency related metabolic crises
Miyake CY, Lay EJ, Beach CM, Ceresnak SR, Delauz CM, Howard TS, Janson CM, Jardine K, Kannankeril PJ, Kava M, Kim JJ, Liberman L, Macicek SL, Pham TD, Robertson T, Valdes SO, Webster G, Stephens SB, Milewicz DM, Azamian M, Ehsan SA, Houck KM, Soler-Alfonso C, Glinton KE, Tosur M, Li N, Xu W, Lalani SR, Zhang L. Cardiac crises: Cardiac arrhythmias and cardiomyopathy during TANGO2 deficiency related metabolic crises. Heart Rhythm 2022, 19: 1673-1681. PMID: 35568137, PMCID: PMC10642301, DOI: 10.1016/j.hrthm.2022.05.009.Peer-Reviewed Original ResearchConceptsVentricular tachycardiaCardiac crisisCardiac arrestMetabolic crisisIntravenous magnesiumAtrial pacingCardiac arrhythmiasRetrospective multicenter chart reviewType I Brugada patternInitiation of feedsMulticenter chart reviewMembrane oxygenation supportCurrent treatment optionsAutosomal recessive diseaseLethal cardiac arrhythmiasBrugada patternOxygenation supportCardiac manifestationsChart reviewQTc prolongationAntiarrhythmic drugsHeart blockSupraventricular tachycardiaTreatment optionsSuccessful treatment
2021
2021 PACES expert consensus statement on the indications and management of cardiovascular implantable electronic devices in pediatric patients
Shah MJ, Silka MJ, Silva JNA, Balaji S, Beach C, Benjamin MN, Berul CI, Cannon B, Cecchin F, Cohen MI, Dalal AS, Dechert BE, Foster A, Gebauer R, Corcia M, Kannankeril J, Karpawich PP, Kim JJ, Krishna MR, Kubuš P, LaPage MJ, Mah DY, Malloy-Walton L, Miyazaki A, Motonaga KS, Niu MC, Olen M, Paul T, Rosenthal E, Saarel EV, Silvetti MS, Stephenson EA, Tan RB, Triedman J, Von Bergen NH, Wackel PL, Fabrizio Drago A. 2021 PACES expert consensus statement on the indications and management of cardiovascular implantable electronic devices in pediatric patients. Cardiology In The Young 2021, 31: 1738-1769. PMID: 34338183, DOI: 10.1017/s1047951121003413.Peer-Reviewed Original ResearchConceptsHeart Rhythm SocietyCardiovascular implantable electronic devicesAsia Pacific Heart Rhythm SocietyLatin American Heart Rhythm SocietyExpert consensus statementAmerican Heart AssociationPediatric patientsImplantable electronic devicesConsensus statementWriting committee membersRare disease entityClass of recommendationLevel of evidenceSpecific disease categoriesYears of ageConsensus expert opinionMiddle-income countriesScience AdvisoryHeart AssociationClinical trialsDisease entityPractice guidelinesEuropean PaediatricAmerican CollegeWriting committee2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients: Executive Summary
Members W, Silka M, Shah M, Silva J, Balaji S, Beach C, Benjamin M, Berul C, Cannon B, Cecchin F, Cohen M, Dalal A, Dechert B, Foster A, Gebauer R, Corcia M, Kannankeril J, Karpawich P, Kim J, Krishna M, Kubuš P, LaPage M, Mah D, Malloy-Walton L, Miyazaki A, Motonaga K, Niu M, Olen M, Paul T, Rosenthal E, Saarel E, Silvetti M, Stephenson E, Tan R, Triedman J, Von Bergen N, Wackel P. 2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients: Executive Summary. Heart Rhythm 2021, 18: 1925-1950. PMID: 34363987, DOI: 10.1016/j.hrthm.2021.07.051.Peer-Reviewed Original Research2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients
Members W, Shah M, Silka M, Silva J, Balaji S, Beach C, Benjamin M, Berul C, Cannon B, Cecchin F, Cohen M, Dalal A, Dechert B, Foster A, Gebauer R, Corcia M, Kannankeril J, Karpawich P, Kim J, Krishna M, Kubuš P, LaPage M, Mah D, Malloy-Walton L, Miyazaki A, Motonaga K, Niu M, Olen M, Paul T, Rosenthal E, Saarel E, Silvetti M, Stephenson E, Tan R, Triedman J, Von Bergen N, Wackel P. 2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients. Heart Rhythm 2021, 18: 1888-1924. PMID: 34363988, DOI: 10.1016/j.hrthm.2021.07.038.Peer-Reviewed Original ResearchConceptsHeart Rhythm SocietyCardiovascular implantable electronic devicesAsia Pacific Heart Rhythm SocietyLatin American Heart Rhythm SocietyExpert consensus statementAmerican Heart AssociationPediatric patientsImplantable electronic devicesConsensus statementWriting committee membersRare disease entityClass of recommendationLevel of evidenceSpecific disease categoriesYears of ageConsensus expert opinionMiddle-income countriesScience AdvisoryHeart AssociationClinical trialsDisease entityPractice guidelinesEuropean PaediatricAmerican CollegeWriting committee2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients Developed in Collaboration With and Endorsed by the Heart Rhythm Society (HRS), the American College of Cardiology (ACC), the American Heart Association (AHA), and the Association for European Paediatric and Congenital Cardiology (AEPC) Endorsed by the Asia Pacific Heart Rhythm Society (APHRS), the Indian Heart Rhythm Society (IHRS), and the Latin American Heart Rhythm Society (LAHRS)
Members W, Shah MJ, Silka MJ, Silva J, Balaji S, Beach C, Benjamin M, Berul C, Cannon B, Cecchin F, Cohen M, Dalal A, Dechert B, Foster A, Gebauer R, Corcia M, Kannankeril J, Karpawich P, Kim J, Krishna MR, Kubuš P, LaPage M, Mah D, Malloy-Walton L, Miyazaki A, Motonaga K, Niu M, Olen M, Paul T, Rosenthal E, Saarel E, Silvetti MS, Stephenson E, Tan R, Triedman J, Von Bergen N, Wackel P. 2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients Developed in Collaboration With and Endorsed by the Heart Rhythm Society (HRS), the American College of Cardiology (ACC), the American Heart Association (AHA), and the Association for European Paediatric and Congenital Cardiology (AEPC) Endorsed by the Asia Pacific Heart Rhythm Society (APHRS), the Indian Heart Rhythm Society (IHRS), and the Latin American Heart Rhythm Society (LAHRS). JACC Clinical Electrophysiology 2021, 7: 1437-1472. PMID: 34794667, DOI: 10.1016/j.jacep.2021.07.009.Peer-Reviewed Original ResearchConceptsAsia Pacific Heart Rhythm SocietyHeart Rhythm SocietyLatin American Heart Rhythm SocietyAmerican Heart AssociationCardiovascular implantable electronic devicesExpert consensus statementPediatric patientsImplantable electronic devicesHeart AssociationConsensus statementEuropean PaediatricAmerican CollegeCongenital cardiologyWriting committee membersRare disease entityClass of recommendationLevel of evidenceSpecific disease categoriesYears of ageConsensus expert opinionMiddle-income countriesScience AdvisoryClinical trialsDisease entityPractice guidelines
2020
Neonatal Cardiac Emergencies: A Multidisciplinary Simulation Curriculum for Neonatology and Pediatric Cardiology Fellows
Simmons MA, Otero-Luna A, Redmond B, Fahey J, Beach C, Bruno C, Johnston L. Neonatal Cardiac Emergencies: A Multidisciplinary Simulation Curriculum for Neonatology and Pediatric Cardiology Fellows. MedEdPORTAL 2020, 16: 11045. PMID: 33365389, PMCID: PMC7751327, DOI: 10.15766/mep_2374-8265.11045.Peer-Reviewed Original ResearchConceptsCardiac diseaseMean overall satisfaction scoreNeonatal cardiac emergencyManagement of neonatesCongenital heart diseaseRemote consultationsPediatric cardiology fellowsOverall satisfaction scoreCardiac concernsCardiogenic shockMultidisciplinary managementUnstable arrhythmiasBedside evaluationPediatric cardiologistsCardiac careHeart diseaseCardiac emergenciesPediatric cardiologyClinical decisionSatisfaction scoresCyanosisNeonatesSimulation curriculumCardiology fellowsDisease
2019
Increasing Burden of Lyme Carditis in United States Children’s Hospitals
Beach CM, Hart SA, Nowalk A, Feingold B, Kurland K, Arora G. Increasing Burden of Lyme Carditis in United States Children’s Hospitals. Pediatric Cardiology 2019, 41: 258-264. PMID: 31728570, DOI: 10.1007/s00246-019-02250-9.Peer-Reviewed Original ResearchConceptsUS children's hospitalsLyme carditisChildren's HospitalLyme diseaseUnited States children's hospitalsSerious cardiac eventsResource utilization dataAdditional diagnostic codesPHIS databaseCardiac eventsDiagnostic codesCarditisHospitalCardiac tropismUtilization dataDiseaseEarly detectionLyme disease incidenceLymeBurdenDisease incidenceHospitalizationEpidemiologyIncidenceCases
2015
Use of three-dimensional mapping in young patients decreases radiation exposure even without a goal of zero fluoroscopy
Beach C, Beerman L, Mazzocco S, Brooks MM, Arora G. Use of three-dimensional mapping in young patients decreases radiation exposure even without a goal of zero fluoroscopy. Cardiology In The Young 2015, 26: 1297-1302. PMID: 26507259, DOI: 10.1017/s1047951115002449.Peer-Reviewed Original ResearchConceptsFluoroscopy timeCatheterisation timeGroup 2Group 3Atrioventricular nodal re-entrant tachycardiaNodal re-entrant tachycardiaRadiation exposureAverage fluoroscopy timeRe-entrant tachycardiaUnadjusted linear regression modelsAcute successYounger patientsComplication rateCryoablation techniqueChronic successRadiofrequency ablationFluoroscopy useGroup 1PatientsCryoablationProgressive decreaseCardiac ablationLinear regression modelsThree-dimensional mappingAblation time