2023
Association of Neighborhood-Level Socioeconomic Factors With Delay to Hospital Arrival in Patients With Acute Stroke
Forman R, Okumu R, Mageid R, Baker A, Neu D, Parker R, Peyravi R, Schindler J, Sansing L, Sheth K, de Havenon A, Jasne A, Narula R, Wira C, Warren J, Sharma R. Association of Neighborhood-Level Socioeconomic Factors With Delay to Hospital Arrival in Patients With Acute Stroke. Neurology 2023, 102: e207764. PMID: 38165368, PMCID: PMC10834135, DOI: 10.1212/wnl.0000000000207764.Peer-Reviewed Original ResearchMeSH KeywordsEmergency Medical ServicesHospitalsHumansIschemic StrokeSocioeconomic FactorsStrokeUnited StatesConceptsEmergency department arrival timesEmergency medical servicesLate presentationAcute ischemic stroke therapyYale-New Haven HospitalGuidelines-Stroke registryNeighborhood-level socioeconomic factorsPatient-level factorsRetrospective observational studyIschemic stroke therapyMixed-effects logistic regression modelNon-white patientsNon-white raceUnivariate logistic regressionNew Haven HospitalLogistic regression modelsHospital presentationTreatment ineligibilityStroke RegistryAcute strokeHospital arrivalStroke therapyUnivariate analysisObservational studyPatientsDiagnosis, Workup, Risk Reduction of Transient Ischemic Attack in the Emergency Department Setting: A Scientific Statement From the American Heart Association
Amin H, Madsen T, Bravata D, Wira C, Johnston S, Ashcraft S, Burrus T, Panagos P, Wintermark M, Esenwa C, Disease O. Diagnosis, Workup, Risk Reduction of Transient Ischemic Attack in the Emergency Department Setting: A Scientific Statement From the American Heart Association. Stroke 2023, 54: e109-e121. PMID: 36655570, DOI: 10.1161/str.0000000000000418.Peer-Reviewed Original ResearchConceptsTransient ischemic attackIschemic attackMaximal medical therapyHigh-risk patientsCorrect clinical diagnosisRisk stratification scaleAmerican Heart AssociationEmergency department settingFuture cerebrovascular eventsScientific statementTime of evaluationCerebrovascular eventsSecondary preventionStroke riskMedical therapyNeurological examinationAcute phaseIndex eventHeart AssociationDepartment settingPatient educationAncillary testingCerebral vasculatureConfirmatory testingClinical diagnosis
2017
Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice: A Brief Narrative Review
McGregor AJ, Beauchamp GA, Wira CR, Perman SM, Safdar B. Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice: A Brief Narrative Review. Western Journal Of Emergency Medicine 2017, 18: 1079-1090. PMID: 29085541, PMCID: PMC5654878, DOI: 10.5811/westjem.2017.8.34997.Peer-Reviewed Original ResearchConceptsClinical practiceAcute ischemic strokeAcute myocardial infarctionEmergency medicineBrief narrative reviewSex-based researchEmergency medicine researchIschemic strokeTherapy administrationPatient sexMyocardial infarctionEmergency carePatient careNarrative reviewEvidence-based researchCase-based scenariosNational InstituteBiological variablesCareSexMedicine researchSABVInfarctionBody of literatureStroke
2016
When to Stop CPR and When to Perform Rhythm Analysis
Giberson B, Uber A, Gaieski D, Miller JB, Wira C, Berg K, Giberson T, Cocchi MN, Abella B, Donnino MW. When to Stop CPR and When to Perform Rhythm Analysis. Journal Of Intensive Care Medicine 2016, 31: 537-543. PMID: 25542192, DOI: 10.1177/0885066614561589.Peer-Reviewed Original ResearchConceptsAdvanced cardiac life supportMajority of respondersUrban tertiary care centerTertiary care centerMinutes of CPRUninterrupted chest compressionsCardiac arrest managementCardiac life supportHealth care providersAdditional therapyCardiac medicationsPalpable pulseRhythm checkCardiac arrestCare centerObservational studyPulse checksCare providersChest compressionsACLS algorithmsResponse rateACLS certificationAdult staff membersMedical providersWeb-based survey
2007
Effective lactate clearance is associated with improved outcome in post-cardiac arrest patients
Donnino MW, Miller J, Goyal N, Loomba M, Sankey SS, Dolcourt B, Sherwin R, Otero R, Wira C. Effective lactate clearance is associated with improved outcome in post-cardiac arrest patients. Resuscitation 2007, 75: 229-234. PMID: 17583412, DOI: 10.1016/j.resuscitation.2007.03.021.Peer-Reviewed Original ResearchConceptsPost-cardiac arrest patientsHigher lactate clearanceArrest patientsLactate clearanceAPACHE II scoreCardiac arrest patientsInitial lactate levelUrban emergency departmentPre-hospital providersEmergency medical servicesHospital mortalityTraumatic arrestHospital courseHospital survivalII scorePrimary endpointHospital dischargeImproved mortalityOverall mortalityMean lactateMultivariable analysisSuccessful resuscitationCardiac arrestEmergency departmentMean age