Dorsal Column Stimulation and Cannabinoids in the Treatment of Chronic Nociceptive and Neuropathic Pain: a Review of the Clinical and Pre-clinical Data
Odonkor CA, AlFarra T, Adekoya P, Orhurhu V, Rodríguez T, Sottosanti E, Kaye AD. Dorsal Column Stimulation and Cannabinoids in the Treatment of Chronic Nociceptive and Neuropathic Pain: a Review of the Clinical and Pre-clinical Data. Current Pain And Headache Reports 2022, 26: 103-118. PMID: 35119602, DOI: 10.1007/s11916-022-01008-y.Peer-Reviewed Original ResearchConceptsSpinal cord stimulationNociceptive painLong-term healthcare costsPain treatment modalitiesDorsal column stimulationPre-clinical dataHigh safety profileCannabinoid-based medicationsPain-signaling pathwaysQuality of lifeMinimal side effectsOpioid consumptionNeuropathic painPain reliefAdjunctive therapySecondary outcomesPain managementCannabinoid therapyClinical efficacyCord stimulationSafety profileCombination therapyFunctional statusTreatment modalitiesFunctional capacity