Featured Publications
Dorsal Column Stimulation and Cannabinoids in the Treatment of Chronic Nociceptive and Neuropathic Pain: a Review of the Clinical and Pre-clinical Data
Odonkor CA, AlFarra T, Adekoya P, Orhurhu V, Rodríguez T, Sottosanti E, Kaye AD. Dorsal Column Stimulation and Cannabinoids in the Treatment of Chronic Nociceptive and Neuropathic Pain: a Review of the Clinical and Pre-clinical Data. Current Pain And Headache Reports 2022, 26: 103-118. PMID: 35119602, DOI: 10.1007/s11916-022-01008-y.Peer-Reviewed Original ResearchConceptsSpinal cord stimulationNociceptive painLong-term healthcare costsPain treatment modalitiesDorsal column stimulationPre-clinical dataHigh safety profileCannabinoid-based medicationsPain-signaling pathwaysQuality of lifeMinimal side effectsOpioid consumptionNeuropathic painPain reliefAdjunctive therapySecondary outcomesPain managementCannabinoid therapyClinical efficacyCord stimulationSafety profileCombination therapyFunctional statusTreatment modalitiesFunctional capacity
2021
Radiofrequency Ablation for Craniofacial Pain Syndromes
Orhurhu V, Sidharthan S, Roberts J, Karri J, Umukoro N, Hagedorn JM, Odonkor CA, Abd-Elsayed A. Radiofrequency Ablation for Craniofacial Pain Syndromes. Physical Medicine And Rehabilitation Clinics Of North America 2021, 32: 601-645. PMID: 34593133, DOI: 10.1016/j.pmr.2021.05.003.Peer-Reviewed Original ResearchInterventional Therapies for Pain in Cancer Patients: a Narrative Review
Hao D, Sidharthan S, Cotte J, Decker M, Salisu-Orhurhu M, Olatoye D, Karri J, Hagedorn JM, Adekoya P, Odonkor C, Gulati A, Orhurhu V. Interventional Therapies for Pain in Cancer Patients: a Narrative Review. Current Pain And Headache Reports 2021, 25: 44. PMID: 33961156, DOI: 10.1007/s11916-021-00963-2.Peer-Reviewed Original ResearchConceptsCancer-related painInterventional therapyCancer patientsNarrative reviewDorsal Root Ganglion StimulationPurpose of ReviewPainOngoing opioid epidemicLess systemic toxicityPeripheral nerve stimulationLives of patientsQuality of lifeOncologic painEffective analgesiaGanglion stimulationNerve stimulationParenteral agentsPrevalent symptomsOpioid abuseSuch therapyOpioid epidemicInterventional approachesInterventional techniquesNeuromodulatory techniquesPainSummaryThe goal
2019
Role of Alpha-2-Microglobulin in the Treatment of Osteoarthritic Knee Pain: a Brief Review of the Literature
Orhurhu V, Schwartz R, Potts J, Peck J, Urits I, Orhurhu MS, Odonkor C, Viswanath O, Kaye A, Gill J. Role of Alpha-2-Microglobulin in the Treatment of Osteoarthritic Knee Pain: a Brief Review of the Literature. Current Pain And Headache Reports 2019, 23: 82. PMID: 31502073, DOI: 10.1007/s11916-019-0822-9.Peer-Reviewed Original ResearchConceptsAnti-inflammatory propertiesAlpha-2 microglobulinOsteoarthritic knee painKnee painPlatelet-rich plasmaCartilage preservationQuality of lifePRP injectionKnee osteoarthritisBody of evidenceActive protease inhibitorsJoint degenerationAnimal modelsPainProtease inhibitorsActive inhibitorTreatmentInhibitorsCurrent understandingPatientsOsteoarthritisReviewActive componentsDegeneration