Intravenous Lidocaine Infusion for the Management of Early Postoperative Pain: A Comprehensive Review of Controlled Trials.
Chu R, Umukoro N, Greer T, Roberts J, Adekoya P, Odonkor CA, Hagedorn JM, Olatoye D, Urits I, Orhurhu MS, Umukoro P, Viswanath O, Hasoon J, Kaye AD, Orhurhu V. Intravenous Lidocaine Infusion for the Management of Early Postoperative Pain: A Comprehensive Review of Controlled Trials. Psychopharmacology Bulletin 2020, 50: 216-259. PMID: 33633427, PMCID: PMC7901134.Peer-Reviewed Original ResearchConceptsEarly postoperative painIntravenous lidocaine infusionSide effectsPostoperative painLidocaine infusionOptimal dosingEarly postoperative pain controlAnti-hyperalgesic effectClear analgesic effectHr continuous infusionPostoperative pain controlCommon side effectsImmediate postoperative periodOpen abdominal surgeryAnti-inflammatory effectsSerious adverse effectsDifferent clinical settingsMechanism of actionIntravenous lidocainePain controlAcute painAnalgesic effectPostoperative periodAbdominal surgeryAntinociceptive effect