2012
Epigenetics and stroke risk – beyond the static DNA code
Marsden P, Matouk C, Turgeon P. Epigenetics and stroke risk – beyond the static DNA code. Advances In Genomics And Genetics 2012, Volume 2: 67-84. DOI: 10.2147/agg.s18697.Peer-Reviewed Original ResearchEpigenetic gene regulationGene regulationPosttranslational modificationsDNA methylationGenetic variationDNA codesGene expressionHigh-throughput genome sequencingChromatin-based mechanismsProtein-coding genesGenome-wide association studiesHistone posttranslational modificationsHistone densityTranscriptional regulationDaughter cellsCell dividesDNA sequencesMolecular basisGenome sequencingAssociation studiesEpigenetic conceptsEpigeneticsRegulationMethylationTrans model
2008
Epigenetic Regulation of Vascular Endothelial Gene Expression
Matouk CC, Marsden PA. Epigenetic Regulation of Vascular Endothelial Gene Expression. Circulation Research 2008, 102: 873-887. PMID: 18436802, DOI: 10.1161/circresaha.107.171025.Peer-Reviewed Original ResearchConceptsVascular endothelial gene expressionEndothelial gene expressionGene expressionChromatin-based pathwaysHistone densityEpigenetic regulationPosttranslational modificationsEpigenetic pathwaysDNA methylationMolecular basisEpigenetic conceptsDisease susceptibilityVascular endothelial cellsVascular biologistsExpressionEndothelial cellsRegulationPathwayEndothelial nitric oxide synthaseBody of evidenceGenomeEpigeneticsMethylationBiologistsRNA