Dysregulated expression of GATA2 and GATA6 transcription factors in adenomyosis: implications for impaired endometrial receptivity
Pavlovic Z, Hsin-Yu Pai A, Hsiao T, Yen C, Alhasan H, Ozmen A, New E, Guo X, Imudia A, Guzeloglu-Kayisli O, Lockwood C, Kayisli U. Dysregulated expression of GATA2 and GATA6 transcription factors in adenomyosis: implications for impaired endometrial receptivity. F&S Science 2023, 5: 92-103. PMID: 37972693, DOI: 10.1016/j.xfss.2023.11.003.Peer-Reviewed Original ResearchHuman endometrial stromal cellsInsulin-like growth factor-binding protein-1Estrogen receptor 1Leukemia inhibitory factorEndometrial stromal cellsProgesterone receptorControl patientsEndometrial sectionsGATA2 overexpressionH-scoreMRNA levelsInhibitory factorStromal cellsGrowth factor-binding protein-1Effect of adenomyosisReproductive-age patientsImpaired endometrial receptivityPotential therapeutic targetYears of ageMessenger RNA levelsEndometrial implantationWestern blot analysisAdenomyosis patientsLIF levelsAge patients