2024
Inflammatory Response and Defects on Myelin Integrity in the Olfactory System of K18hACE2 Mice Infected with SARS-CoV-2
Martin-Lopez E, Brennan B, Mao T, Spence N, Meller S, Han K, Yahiaoui N, Wang C, Iwasaki A, Greer C. Inflammatory Response and Defects on Myelin Integrity in the Olfactory System of K18hACE2 Mice Infected with SARS-CoV-2. ENeuro 2024, 11: eneuro.0106-24.2024. PMID: 38834299, PMCID: PMC11185043, DOI: 10.1523/eneuro.0106-24.2024.Peer-Reviewed Original ResearchOlfactory bulbOlfactory epitheliumPiriform cortexOlfactory tractOlfactory systemSARS-CoV-2Projection neuronsMyelination defectsOlfactory sensory neuronsLateral olfactory tractLoss of olfactionRespiratory epithelial cellsLamina propria macrophagesSARS-CoV-2 infectionInfected SCDays of infectionIntegrity of myelinOlfactory dysfunctionInfected microgliaSensitive to infectionOlfactory deficitsSensory neuronsSustentacular cellsNasal cavityNeuronal conduction
2014
Nonsensory target-dependent organization of piriform cortex
Chen CF, Zou DJ, Altomare CG, Xu L, Greer CA, Firestein SJ. Nonsensory target-dependent organization of piriform cortex. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 16931-16936. PMID: 25385630, PMCID: PMC4250170, DOI: 10.1073/pnas.1411266111.Peer-Reviewed Original ResearchConceptsPiriform cortexOrbitofrontal cortexMouse piriform cortexOutput neuronsPrimary sensory cortexAssociation fiber systemsFluorescent retrograde tracingLateral orbitofrontal cortexRetrograde tracingEfferent componentsEfferent pathwaysAfferent inputEfferent projectionsOlfactory cortexOlfactory bulbAgranular insulaSensory cortexEfferent circuitsCortex
2010
Developmental Dynamics of Piriform Cortex
Sarma AA, Richard MB, Greer CA. Developmental Dynamics of Piriform Cortex. Cerebral Cortex 2010, 21: 1231-1245. PMID: 21041199, PMCID: PMC3140179, DOI: 10.1093/cercor/bhq199.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnalysis of VarianceAnimalsAnimals, NewbornBromodeoxyuridineCell DifferentiationCerebral CortexEmbryo, MammalianFemaleGene Expression Regulation, DevelopmentalGlutamate DecarboxylaseGreen Fluorescent ProteinsIndolesMiceMice, TransgenicNerve Tissue ProteinsNeuronsNonlinear DynamicsPregnancyRatsConceptsAnterior piriform cortexPiriform cortexPyramidal cellsLayers IIPostnatal developmentCortical sensory processingNumber of interneuronsMolecular maturationCortical laminationInhibitory synapsesPostnatal eventsInhibitory networksSensory processingOdor codingPaleocortexCortexMorphological basisCellsMaturationInterneuronsNeocortexSynapses