2005
Neural circuitry of judgment and decision mechanisms
Opris I, Bruce CJ. Neural circuitry of judgment and decision mechanisms. Brain Research Reviews 2005, 48: 509-526. PMID: 15914255, DOI: 10.1016/j.brainresrev.2004.11.001.Peer-Reviewed Original ResearchConceptsDecision formationNeural circuitrySystems neuroscience approachHigher cognitive functionsOptimal behavioral responseNeuroscience approachResponse selectionReward expectationDecision mechanismCognitive functionNeural activitySensory inputBehavioral outputPrimate brainPrior experienceBehavioral responsesSubcortical areasDeliberation processCortical loopDecision circuitCircuitryJudgmentsDynamic interactionActivation thresholdSelection bias
1995
Comparison of the smooth eye tracking disorder of schizophrenics with that of nonhuman primates with specific brain lesions
Macavoy M, Bruce C. Comparison of the smooth eye tracking disorder of schizophrenics with that of nonhuman primates with specific brain lesions. International Journal Of Neuroscience 1995, 80: 117-151. PMID: 7775044, DOI: 10.3109/00207459508986097.Peer-Reviewed Original ResearchConceptsEye tracking deficitsTracking deficitsLow gain pursuitFirst-degree relativesSpecific brain lesionsFrontal lobe theoryNeuroleptic medicationIntrusive saccadesBrain lesionsDegree relativesBrain areasFrontal lobeExperimental lesionsLesionsSchizophreniaSchizophrenicsDeficitsSaccadesFurther supportMedicationsReview
1987
A sequential double-label 14C- and 3H-2-DG technique: validation by double-dissociation of functional states
Friedman H, Bruce C, Goldman-Rakic P. A sequential double-label 14C- and 3H-2-DG technique: validation by double-dissociation of functional states. Experimental Brain Research 1987, 66: 543-554. PMID: 3609200, DOI: 10.1007/bf00270687.Peer-Reviewed Original ResearchConceptsDose ratioFunctional stateX-ray filmsBrain metabolismDouble-label methodBrain sectionsOwn controlSame animalsTreatmentInjectionComputerized imaging systemUltrofilmSame subjectsUptake patternsMetabolic activityInitial studyAutoradiogramsSubjectsDifferent functional statesUptakeExperimental treatmentsDifferent treatmentsRatsActivityCases