2000
Supplementary Eye Field: Representation of Saccades and Relationship Between Neural Response Fields and Elicited Eye Movements
Russo G, Bruce C. Supplementary Eye Field: Representation of Saccades and Relationship Between Neural Response Fields and Elicited Eye Movements. Journal Of Neurophysiology 2000, 84: 2605-2621. PMID: 11068002, DOI: 10.1152/jn.2000.84.5.2605.Peer-Reviewed Original ResearchConceptsSupplementary eye fieldElicited saccadesEye fieldElicited eye movementsSaccade directionVisual field coordinatesPeripheral target locationFrontal eye fieldNeural response fieldsVisual receptive fieldsVisuomovement neuronsCentral fixation pointPresaccadic activityOculomotor structuresContralateral saccadesOculomotor functionDirection of saccadesSuperior colliculusNeural dischargeSEF neuronsCentral fixationResponse fieldSaccade amplitudeSaccadesNeurons
1998
Deficits in Smooth-Pursuit Eye Movements After Muscimol Inactivation Within the Primate's Frontal Eye Field
Shi D, Friedman H, Bruce C. Deficits in Smooth-Pursuit Eye Movements After Muscimol Inactivation Within the Primate's Frontal Eye Field. Journal Of Neurophysiology 1998, 80: 458-464. PMID: 9658064, DOI: 10.1152/jn.1998.80.1.458.Peer-Reviewed Original ResearchConceptsFrontal eye fieldSmooth eye movement regionPrimate frontal eye fieldMuscimol injectionsArcuate sulcusEye fieldGamma-aminobutyric acid agonistSP deficitsSmooth pursuit eye movementsMicroinjection of muscimolSmooth pursuit functionMuscimol inactivationEye movement directionInjected hemisphereReversible deficitsFEFsemPermanent deficitsNeuronal responsesPosterior bankAspiration lesionsLarge aspiration lesionsEye movementsMotion onsetNext dayMuscimol
1997
Suppression of Task-Related Saccades by Electrical Stimulation in the Primate's Frontal Eye Field
Burman D, Bruce C. Suppression of Task-Related Saccades by Electrical Stimulation in the Primate's Frontal Eye Field. Journal Of Neurophysiology 1997, 77: 2252-2267. PMID: 9163356, DOI: 10.1152/jn.1997.77.5.2252.Peer-Reviewed Original ResearchConceptsFrontal eye fieldPrimate frontal eye fieldSaccadic eye movementsElectrical stimulationEye fieldFEF sitesFoveal receptive fieldsSuppression of saccadesLow-intensity stimulationEye movementsCentral fixation targetMemory-guided saccadesAppropriate saccadeCortex anteriorFEF projectionsContraversive saccadesAnterior bankIntracortical microstimulationStimulation trialsPremotor cortexEvidence of suppressionReflexive saccadesMacaque monkeysSubcortical regionsFrontal lobe damage
1995
Topography of projections to posterior cortical areas from the macaque frontal eye fields
Stanton G, Bruce C, Goldberg M. Topography of projections to posterior cortical areas from the macaque frontal eye fields. The Journal Of Comparative Neurology 1995, 353: 291-305. PMID: 7745137, DOI: 10.1002/cne.903530210.Peer-Reviewed Original ResearchConceptsMedial superior temporal areaSuperior temporal polysensory areaVentral intraparietal areaLateral intraparietal areaMiddle temporal areaInferior temporal areasCortical areasTemporal-occipital areasTemporal areaMedial partArea MSTEye fieldIntraparietal areaArea PEVisual areasArea lateral intraparietal areaArea V2Macaque frontal eye fieldArea MTArea 23bParietal area 7aTemporal visual areaTopography of projectionsFrontal eye fieldSuperior temporal area
1994
Physiological correlate of fixation disengagement in the primate's frontal eye field
Dias E, Bruce C. Physiological correlate of fixation disengagement in the primate's frontal eye field. Journal Of Neurophysiology 1994, 72: 2532-2537. PMID: 7884478, DOI: 10.1152/jn.1994.72.5.2532.Peer-Reviewed Original ResearchConceptsFrontal eye fieldPresaccadic activityEye fieldPrimate frontal eye fieldMs. 3Short-latency saccadesGap taskDisengagement of fixationFixation disengagementVisuomovement cellsExpress saccadesFEF neuronsMean latencyFixation targetSaccade latencyRhesus monkeysSaccade taskSaccadic targetTrialsResponse fieldSaccadesSaccade targetCell fieldNeuronsFixation pointNeural responses related to smooth-pursuit eye movements and their correspondence with electrically elicited smooth eye movements in the primate frontal eye field
Gottlieb J, MacAvoy M, Bruce C. Neural responses related to smooth-pursuit eye movements and their correspondence with electrically elicited smooth eye movements in the primate frontal eye field. Journal Of Neurophysiology 1994, 72: 1634-1653. PMID: 7823092, DOI: 10.1152/jn.1994.72.4.1634.Peer-Reviewed Original ResearchConceptsSmooth eye movementsFrontal eye fieldPursuit neuronsEye movementsEye fieldPosterior bankPursuit directionPrimate frontal eye fieldMonkey frontal eye fieldSmooth pursuit eye movementsDirectional tuningBroad directional tuningSaccadic eye movementsSmooth pursuit trackingPursuit cellsMost neuronsIntracortical microstimulationPursuit velocityFEF neuronsFEF regionSmooth pursuitRhesus monkeysRegion involvementNeuron responsesNeuronsFrontal eye field activity preceding aurally guided saccades
Russo G, Bruce C. Frontal eye field activity preceding aurally guided saccades. Journal Of Neurophysiology 1994, 71: 1250-1253. PMID: 8201415, DOI: 10.1152/jn.1994.71.3.1250.Peer-Reviewed Original ResearchConceptsFrontal eye fieldSaccade-related burst neuronsAuditory targetsMonkey frontal eye fieldVisual targetsFrontal eye field activityMovement fieldsGoal-directed saccadesVisuomovement cellsBurst neuronsIntracortical microstimulationSuch saccadesFEF activityFEF neuronsNeuronal activitySuperior colliculusEye fieldSaccadesSaccadic processingNeuronsComparable burstsMovement cellsCellsFixation directionTarget
1993
Topography of projections to the frontal lobe from the macaque frontal eye fields
Stanton G, Bruce C, Goldberg M. Topography of projections to the frontal lobe from the macaque frontal eye fields. The Journal Of Comparative Neurology 1993, 330: 286-301. PMID: 8491870, DOI: 10.1002/cne.903300209.Peer-Reviewed Original ResearchConceptsFrontal eye fieldArcuate sulcusFrontal lobePrincipal sulcusInjection siteEye fieldIpsilateral frontal lobeMacaque frontal eye fieldTopography of projectionsSaccadic eye movementsTracer injection siteFEF areaFEF projectionsAnterior wallPosterior wallSubcortical connectionsElectrical elicitationMedial partUpper limbMacaque monkeysCortical layersSmall saccadesDorsomedial convexitySulcusEye movementsSmooth eye movements elicited by microstimulation in the primate frontal eye field
Gottlieb J, Bruce C, MacAvoy M. Smooth eye movements elicited by microstimulation in the primate frontal eye field. Journal Of Neurophysiology 1993, 69: 786-799. PMID: 8385195, DOI: 10.1152/jn.1993.69.3.786.Peer-Reviewed Original ResearchConceptsSmooth eye movementsFrontal eye field regionFixation targetEye movementsStimulation intensityPursuit systemPrimate frontal eye fieldCortex. 5Frontal eye fieldPeak velocityTrains of stimulationAverage peak velocityDegrees/sStationary fixation targetIpsilateral movementsMs. 2Principal sulcusEye velocityRetinal slipAdult monkeysElectrical stimulationEye fieldPosterior bankElectrode penetrationsStimulation siteEffect of eye position within the orbit on electrically elicited saccadic eye movements: a comparison of the macaque monkey's frontal and supplementary eye fields
Russo G, Bruce C. Effect of eye position within the orbit on electrically elicited saccadic eye movements: a comparison of the macaque monkey's frontal and supplementary eye fields. Journal Of Neurophysiology 1993, 69: 800-818. PMID: 8385196, DOI: 10.1152/jn.1993.69.3.800.Peer-Reviewed Original Research
1991
Smooth-Pursuit Eye Movement Representation in the Primate Frontal Eye Field
MacAvoy M, Gottlieb J, Bruce C. Smooth-Pursuit Eye Movement Representation in the Primate Frontal Eye Field. Cerebral Cortex 1991, 1: 95-102. PMID: 1822728, DOI: 10.1093/cercor/1.1.95.Peer-Reviewed Original ResearchConceptsSmooth pursuit eye movementsFrontal eye fieldPrimate frontal eye fieldEye movementsEye fieldIpsilateral smooth pursuitElicit eye movementsSaccadic eye movementsElicited saccadesSmooth pursuitSuperficial lesionsExperimental lesionsTracking deficitsLesionsVentral regionSubstantial deficitsVisual motionMovement representationsDeficitsMicrostimulationNeurons
1990
Primate frontal eye fields. III. Maintenance of a spatially accurate saccade signal
Goldberg M, Bruce C. Primate frontal eye fields. III. Maintenance of a spatially accurate saccade signal. Journal Of Neurophysiology 1990, 64: 489-508. PMID: 2213128, DOI: 10.1152/jn.1990.64.2.489.Peer-Reviewed Original ResearchConceptsFrontal eye fieldDouble-step taskSaccadic eye movementsEye fieldPostsaccadic activitySecond saccadeEye movementsFirst saccadeMonkey frontal eye fieldRetinal coordinatesDouble-step paradigmRetina. 2Receptive fieldsMovement fieldsVisuomovement cellsCell receptive fieldsPresaccadic activityMovement cellsFlashed targetsSaccade signalOculomotor tasksNeuronsSingle neuronsSaccadesRetinal stimulation
1988
Frontal eye field efferents in the macaque monkey: I. Subcortical pathways and topography of striatal and thalamic terminal fields
Stanton G, Goldberg M, Bruce C. Frontal eye field efferents in the macaque monkey: I. Subcortical pathways and topography of striatal and thalamic terminal fields. The Journal Of Comparative Neurology 1988, 271: 473-492. PMID: 2454970, DOI: 10.1002/cne.902710402.Peer-Reviewed Original ResearchMeSH KeywordsAmino AcidsAnimalsAutoradiographyBrain MappingCorpus StriatumEfferent PathwaysElectric StimulationEye MovementsHorseradish PeroxidaseMacacaMacaca fascicularisMacaca mulattaOculomotor MusclesThalamusVisual FieldsWheat Germ Agglutinin-Horseradish Peroxidase ConjugateWheat Germ AgglutininsConceptsFrontal eye fieldMedial dorsal nucleusTerminal fieldsInjection siteDorsal nucleusSubthalamic nucleusCaudate nucleusMacaque monkeysArea 6Thalamic terminal fieldsArea XSaccadic eye movementsAmplitude of saccadesPars parvicellularisSubthalamic pathwayInternal capsuleExternal capsuleThalamic nucleiAnterograde tracerVentrolateral partVentromedial partCaudate bodyDorsomedial portionSubcortical pathwaysCaudal part
1986
The effect of attentive fixation on eye movements evoked by electrical stimulation of the frontal eye fields
Goldberg M, Bushnell M, Bruce C. The effect of attentive fixation on eye movements evoked by electrical stimulation of the frontal eye fields. Experimental Brain Research 1986, 61: 579-584. PMID: 3956616, DOI: 10.1007/bf00237584.Peer-Reviewed Original ResearchConceptsFrontal eye fieldEye fieldElectrical stimulationActive fixationAttentive fixationEye movementsVisual fixation targetBehavioral statesCerebral cortexEye velocityElicited saccadesLarge saccadesState of fixationFixation targetRhesus monkeysStimulating electrodesOculomotor systemEye positionSaccade amplitudeSaccadesVisual targetsStimulationMonkeysFixationResponsible factorsThe role of the arcuate frontal eye fields in the generation of saccadic eye movements
Goldberg M, Bruce C. The role of the arcuate frontal eye fields in the generation of saccadic eye movements. Progress In Brain Research 1986, 64: 143-154. PMID: 3726143, DOI: 10.1016/s0079-6123(08)63409-3.Peer-Reviewed Original Research
1985
Primate frontal eye fields. II. Physiological and anatomical correlates of electrically evoked eye movements
Bruce C, Goldberg M, Bushnell M, Stanton G. Primate frontal eye fields. II. Physiological and anatomical correlates of electrically evoked eye movements. Journal Of Neurophysiology 1985, 54: 714-734. PMID: 4045546, DOI: 10.1152/jn.1985.54.3.714.Peer-Reviewed Original ResearchConceptsFrontal eye fieldEye fieldArcuate sulcusPresaccadic neuronsSaccade directionArea 8Frontal eye field neuronsEye movementsBrodmann area 8Cortical gray matterSaccadic eye movementsAwake macaque monkeysArea 8APresaccadic activityAnterior bankVentrolateral portionDorsomedial portionElicited saccadesElectrical stimulationLarge saccadesMacaque monkeysGray matterElectrode penetrationsAnatomical correlatesSmall saccadesCerebral cortical activity associated with the orientation of visual attention in the rhesus monkey
Goldberg M, Bruce C. Cerebral cortical activity associated with the orientation of visual attention in the rhesus monkey. Vision Research 1985, 25: 471-481. PMID: 4024466, DOI: 10.1016/0042-6989(85)90072-0.Peer-Reviewed Original ResearchConceptsFrontal eye fieldPosterior parietal cortexEye fieldParietal cortexRhesus monkeysCerebral cortical activitySingle neuron dischargesPurposive saccadesNeuron dischargePredictable saccadesCortical activitySaccadesMonkeysEnhanced responseCortexVisual stimuliVisual guidanceStimuliDischargeNeuronsResponse
1984
Physiology of the frontal eye fields
Bruce C, Goldberg M. Physiology of the frontal eye fields. Trends In Neurosciences 1984, 7: 436-441. DOI: 10.1016/s0166-2236(84)80149-6.Peer-Reviewed Original Research