1995
Relative expression of the human epithelial Na+ channel subunits in normal and cystic fibrosis airways
Burch L, Talbot C, Knowles M, Canessa C, Rossier B, Boucher R. Relative expression of the human epithelial Na+ channel subunits in normal and cystic fibrosis airways. American Journal Of Physiology 1995, 269: c511-c518. PMID: 7653534, DOI: 10.1152/ajpcell.1995.269.2.c511.Peer-Reviewed Original ResearchConceptsAirway epitheliumSuperficial epitheliumCF airwaysGamma-ENaC mRNACF airway diseaseENaC subunit mRNAsCystic fibrosis airway epitheliaCF airway epitheliaAirway diseaseSitu hybridization studiesDuctal epitheliumCF transmembrane conductance regulator (CFTR) proteinRibonuclease protection assaysAcinar epitheliumMolecular pathogenesisCystic fibrosisChannel mRNAInhibitory regulationSubunit mRNAsEpitheliumChannel subunitsRatio of alphaAirwayRelative expressionPathogenesis
1993
Expression of the epithelial Na+ channel in the developing rat lung
O'Brodovich H, Canessa C, Ueda J, Rafii B, Rossier B, Edelson J. Expression of the epithelial Na+ channel in the developing rat lung. American Journal Of Physiology 1993, 265: c491-c496. PMID: 7690185, DOI: 10.1152/ajpcell.1993.265.2.c491.Peer-Reviewed Original ResearchConceptsFetal lungAlveolar epitheliumRat lungAdult lungThyroid-releasing hormoneRat colonic epitheliumAlpha-rENaCWhole rat lungRat whole kidneyCombined administrationPregnant ratsImmature lungLung alphaAlveolar spaceColonic epitheliumLower mRNA levelsWhole kidneyLungSaccular stageLung developmentAdult alveolar epitheliumPrimary culturesDays GAEpitheliumMRNA levels