Regulation of aldosterone secretion by Cav1.3
Xie CB, Haris Shaikh L, Garg S, Tanriver G, Teo AE, Zhou J, Maniero C, Zhao W, Kang S, Silverman RB, Azizan EA, Brown MJ. Regulation of aldosterone secretion by Cav1.3. Scientific Reports 2016, 6: 24697. PMID: 27098837, PMCID: PMC4876952, DOI: 10.1038/srep24697.Peer-Reviewed Original ResearchConceptsAldosterone-producing adenomaH295R cellsL-type calcium channel Cav1.3Role of Cav1.3Human adrenocortical cell lineVascular side effectsHuman adrenal cellsAdrenocortical cell lineAldosterone secretionAntihypertensive drug nifedipinePrimary hyperaldosteronismAldosterone productionZona glomerulosaInvestigational drugsSide effectsChannel Cav1.3Cav1.3Adrenal cellsCav1.3 channelsNovel antagonistCell linesNifedipineDrug nifedipineCompound 8Cells