Microvessel area using automated image analysis is reproducible and is associated with prognosis in breast cancer
Sullivan CA, Ghosh S, Ocal IT, Camp RL, Rimm DL, Chung GG. Microvessel area using automated image analysis is reproducible and is associated with prognosis in breast cancer. Human Pathology 2008, 40: 156-165. PMID: 18799189, DOI: 10.1016/j.humpath.2008.07.005.Peer-Reviewed Original ResearchConceptsVIII-related antigenMicrovessel densityMicrovessel areaBreast cancerFactor VIII-related antigenPrimary breast cancerEstrogen receptor negativityReceptor negativityNode positivityClinical outcomesEvaluable casesPrognostic parametersAngiogenic biomarkersLarge tumorsYear survivalQuantitative image analysis systemTissue microarrayTumorsCD31Multivariate levelVessel compartmentPoor associationCancerAntigenCD34Biomarker Validation: In Situ Analysis of Protein Expression Using Semiquantitative Immunohistochemistry-Based Techniques
Sullivan CA, Chung GG. Biomarker Validation: In Situ Analysis of Protein Expression Using Semiquantitative Immunohistochemistry-Based Techniques. Clinical Colorectal Cancer 2008, 7: 172-177. PMID: 18621634, DOI: 10.3816/ccc.2008.n.022.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkers, TumorGene Expression ProfilingGenomicsHumansImmunohistochemistryProteomicsTissue Array AnalysisConceptsProteomic high-throughput technologiesProtein expressionExpression profile dataHigh-throughput technologiesDrug development targetsMicroarray technologyImmunohistochemistry-based assessmentArchived samplesCancer researchExpressionTissue microarray technologyTissue samplesAbundanceSitu analysisAbundance of data