Intense Expression of the B7-2 Antigen Presentation Coactivator Is an Unfavorable Prognostic Indicator for Differentiated Thyroid Carcinoma of Children and Adolescents
Shah R, Banks K, Patel A, Dogra S, Terrell R, Powers PA, Fenton C, Dinauer CA, Tuttle RM, Francis GL. Intense Expression of the B7-2 Antigen Presentation Coactivator Is an Unfavorable Prognostic Indicator for Differentiated Thyroid Carcinoma of Children and Adolescents. The Journal Of Clinical Endocrinology & Metabolism 2002, 87: 4391-4397. PMID: 12213904, DOI: 10.1210/jc.2002-011262.Peer-Reviewed Original ResearchConceptsB7-2 expressionThyroid carcinomaLymphocytic infiltrationB7-1B7-2Immune responseAdjacent thyroidImproved disease-free survivalDisease-free survivalTumor-associated lymphocytesDifferentiated thyroid carcinomaProbability of remissionUnfavorable prognostic indicatorB7-1 expressionFollicular thyroid carcinomaLong-term survivalHigh-power fieldBenign thyroid lesionsPrognostic indicatorThyroid diseaseAntigen presentationBenign tumorsMalignant tumorsCarcinomaThyroid lesions