2001
Serum hepatic biochemical activity in two populations of workers exposed to styrene
Brodkin C, Moon J, Camp J, Echeverria D, Redlich C, Willson R, Checkoway H. Serum hepatic biochemical activity in two populations of workers exposed to styrene. Occupational And Environmental Medicine 2001, 58: 95. PMID: 11160987, PMCID: PMC1740098, DOI: 10.1136/oem.58.2.95.Peer-Reviewed Original ResearchConceptsTotal bilirubin ratioSignificant linear associationHepatic clearancePooled analysisDirect bilirubinBilirubin ratioConjugated bilirubinIndependent cross-sectional studiesHepatic biochemical changesHepatic biochemical variablesHepatic transaminase concentrationsMild hepatic injuryLinear associationBody mass indexSerum hepatic transaminasesExposure-response trendsCross-sectional studySignificant exposure-response trendDirect bilirubin concentrationsAssociated cholestasisBlood styreneCholestatic enzymesHepatic transaminasesHepatic injuryMass index
1988
Liver disease associated with occupational exposure to the solvent dimethylformamide.
Redlich C, Beckett W, Sparer J, Barwick K, Riely C, Miller H, Sigal S, Shalat S, Cullen M. Liver disease associated with occupational exposure to the solvent dimethylformamide. Annals Of Internal Medicine 1988, 108: 680-6. PMID: 3358569, DOI: 10.7326/0003-4819-108-5-680.Peer-Reviewed Original ResearchConceptsToxic liver diseaseLiver enzyme abnormalitiesLiver diseaseEnzyme abnormalitiesAspartate aminotransferaseALT levelsBiopsy specimensStandard liver function testsAppropriate skin protectionClinical-epidemiological investigationNegative viral serologyOccupational liver diseaseSymptoms of hepatitisEnzyme levelsLiver function testsLiver biopsy specimensRatio of ASTToxic liver injuryOccupational medicine clinicExtensive clinical evaluationAcademic medical centerViral serologyAminotransferase levelsMost patientsLiver injury