Dietary vitamin A and prevalence of bronchial metaplasia in asbestos-exposed workers 1 2 3
Mayne ST, Redlich CA, Cullen MR. Dietary vitamin A and prevalence of bronchial metaplasia in asbestos-exposed workers 1 2 3. American Journal Of Clinical Nutrition 1998, 68: 630-636. PMID: 9734740, DOI: 10.1093/ajcn/68.3.630.Peer-Reviewed Original ResearchConceptsTotal vitamin ABronchial metaplasiaVitamin AAsbestos workersDietary intakeHigh intakeBronchial squamous metaplasiaGreater airway obstructionPulmonary function testingDietary vitamin ALogistic regression analysisAirway obstructionFormer smokingCurrent smokingBronchial biopsiesTobacco exposureSquamous metaplasiaFunction testingAsbestos exposureForm of retinolNonsignificant reductionLow intakeMetaplasiaNonsignificant increaseIndustrial clinicsEffect of supplementation with beta-carotene and vitamin A on lung nutrient levels.
Redlich CA, Blaner WS, Van Bennekum AM, Chung JS, Clever SL, Holm CT, Cullen MR. Effect of supplementation with beta-carotene and vitamin A on lung nutrient levels. Cancer Epidemiology Biomarkers & Prevention 1998, 7: 211-4. PMID: 9521435.Peer-Reviewed Original ResearchConceptsActive armRetinol levelsLung tissueExcess lung cancer mortalityLung cancer chemoprevention trialsLung retinol levelsRetinol Efficacy TrialLung tissue levelsLung cancer mortalityCancer chemoprevention trialsEffect of supplementationLung retinolChemoprevention trialsCancer mortalitySurgical controlEfficacy trialsCell levelVitamin ARetinyl palmitateSame interventionTissue levelsBiomarker studiesSupplementationInterventionTrials