Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: detection by the polymerase chain reaction.
Omiecinski C, Redlich C, Costa P. Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: detection by the polymerase chain reaction. Cancer Research 1990, 50: 4315-21. PMID: 1694720.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsBase SequenceBlotting, NorthernBlotting, SouthernCytochrome P-450 Enzyme SystemDNAGene Expression Regulation, EnzymologicGenesIsoenzymesLiverMethylcholanthreneMolecular Sequence DataOligonucleotide ProbesOrgan SpecificityPhenobarbitalPolymerase Chain ReactionRatsRats, Inbred StrainsReference ValuesRNARNA, MessengerConceptsPolymerase chain reactionHuman pulmonary alveolar macrophagesChain reactionP450IA1 mRNAEarly gestational stageEnvironmental chemical exposuresPulmonary alveolar macrophagesDevelopmental ageTransplacental treatmentFetal ratsHuman gestationGestational stagesRat lungAlveolar macrophagesDay 15Related cancersHuman tissue samplesIndividual susceptibilityDay 45Fetal liver developmentTarget cellsMRNA expression patternsRatsTissue samplesChemical exposure