Polyisocyanates and Their Prepolymers
Jolly A, Maestrelli P, Redlich C, Malo J, Bernstein D. Polyisocyanates and Their Prepolymers. 2021, 179-194. DOI: 10.1201/9781003000624-14.ChaptersOccupational asthmaHuman leukocyte antigenAirway inflammationDiisocyanate-induced occupational asthmaSensitizer-induced occupational asthmaWeight agentsOnset of asthmaOnset of symptomsLong-term outcomesMedical surveillance programNon-HLA genesReduction of exposureAverage exposure levelsAirway hyperresponsivenessSevere asthmaAsthmatic symptomsClinical presentationNeutrophilic infiltrateLeukocyte antigenClinical assessmentDifferent exposure metricsIrritant concentrationsHigh riskMechanism of sensitizationIsocyanate exposure