Clinical and pathological characteristics of hepatotoxicity associated with occupational exposure to dimethylformamide
Redlich C, West A, Fleming L, True L, Cullen M, Riely C. Clinical and pathological characteristics of hepatotoxicity associated with occupational exposure to dimethylformamide. Gastroenterology 1990, 99: 748-757. PMID: 2379779, DOI: 10.1016/0016-5085(90)90964-3.Peer-Reviewed Original ResearchConceptsToxic liver injuryLiver injuryDisulfiram-type reactionsFocal hepatocellular necrosisSmooth endoplasmic reticulumProminent smooth endoplasmic reticulumAbnormal aminotransferasesAbdominal painBiopsy findingsClinical characteristicsEnzyme elevationLiver biopsyPleomorphic mitochondriaAcute injuryHepatocellular necrosisMicrovesicular steatosisBiopsy histologyMacrovesicular steatosisPathological characteristicsOccupational exposureAlanine aminotransferaseOccupational historyLonger exposureInjuryAminotransferase