2022
Gender-related association among childhood maltreatment, brain structure and clinical features in bipolar disorder
Colic L, Clark A, Sankar A, Rathi DJ, Goldman DA, Kim JA, Villa LM, Edmiston EK, Lippard ETC, Pittman B, Constable RT, Mazure CM, Blumberg HP. Gender-related association among childhood maltreatment, brain structure and clinical features in bipolar disorder. European Neuropsychopharmacology 2022, 63: 35-46. PMID: 36037590, PMCID: PMC9593266, DOI: 10.1016/j.euroneuro.2022.07.186.Peer-Reviewed Original ResearchConceptsClinical featuresBipolar disorderCM severityChildhood maltreatmentLeft hippocampusPost-traumatic stress disorder (PTSD) comorbidityBrain structuresStructural magnetic resonance imagingGender-related associationMagnetic resonance imagingGray matter structuresChildhood Trauma QuestionnaireGender-related differencesCM exposureHealthy controlsClinical assessmentDisorder comorbidityMood symptomsPathophysiological modelGender-related effectsResonance imagingHippocampusFrontal poleTrauma QuestionnaireSeverity
2021
Mental Health and Wealth: Depression, Gender, Poverty, and Parenting
Smith MV, Mazure CM. Mental Health and Wealth: Depression, Gender, Poverty, and Parenting. Annual Review Of Clinical Psychology 2021, 17: 181-205. PMID: 33962537, DOI: 10.1146/annurev-clinpsy-071219-022710.Peer-Reviewed Original Research
2019
It all adds up: Addressing the roles of cumulative traumatic experiences on military veterans
Scoglio AAJ, Shirk SD, Mazure C, Park CL, Molnar BE, Hoff RA, Kraus SW. It all adds up: Addressing the roles of cumulative traumatic experiences on military veterans. Child Abuse & Neglect 2019, 98: 104227. PMID: 31648113, DOI: 10.1016/j.chiabu.2019.104227.Peer-Reviewed Original Research
2011
Corticostriatal-Limbic Gray Matter Morphology in Adolescents With Self-reported Exposure to Childhood Maltreatment
Edmiston EE, Wang F, Mazure CM, Guiney J, Sinha R, Mayes LC, Blumberg HP. Corticostriatal-Limbic Gray Matter Morphology in Adolescents With Self-reported Exposure to Childhood Maltreatment. JAMA Pediatrics 2011, 165: 1069-1077. PMID: 22147775, PMCID: PMC3607102, DOI: 10.1001/archpediatrics.2011.565.Peer-Reviewed Original ResearchChildhood abuse and neglect and cognitive flexibility in adolescents
Spann MN, Mayes LC, Kalmar JH, Guiney J, Womer FY, Pittman B, Mazure CM, Sinha R, Blumberg HP. Childhood abuse and neglect and cognitive flexibility in adolescents. Child Neuropsychology 2011, 18: 182-189. PMID: 21942637, PMCID: PMC3326262, DOI: 10.1080/09297049.2011.595400.Peer-Reviewed Original ResearchConceptsWisconsin Card Sorting TestCognitive flexibilityPerseverative errorsChildhood maltreatmentChildhood Trauma QuestionnaireExecutive functionNonperseverative errorsExecutive dysfunctionPhysical neglectPhysical abusePerseverative error scoresImpaired school functioningCard Sorting TestSelf-report Childhood Trauma QuestionnaireSelf-reported childhood maltreatmentAdolescents ages 12Total CTQ scoresExecutive functioningCTQ total scoresSorting TestSchool functioningAxis I DisordersEmotional abuseCorrelational analysisChildhood abuse
2007
Severity of childhood trauma is predictive of cocaine relapse outcomes in women but not men
Hyman SM, Paliwal P, Chaplin TM, Mazure CM, Rounsaville BJ, Sinha R. Severity of childhood trauma is predictive of cocaine relapse outcomes in women but not men. Drug And Alcohol Dependence 2007, 92: 208-216. PMID: 17900822, PMCID: PMC2233653, DOI: 10.1016/j.drugalcdep.2007.08.006.Peer-Reviewed Original ResearchMeSH KeywordsAdultAdult Survivors of Child AbuseChildChild Abuse, SexualCocaine-Related DisordersData Interpretation, StatisticalFemaleFollow-Up StudiesHumansInpatientsMaleMiddle AgedPredictive Value of TestsProspective StudiesPsychiatric Status Rating ScalesRecurrenceSex CharacteristicsSocioeconomic FactorsSubstance Abuse Treatment CentersSurveys and QuestionnairesConceptsOverall childhood traumaCocaine relapse outcomesChildhood traumaEmotional abuseRelapse outcomesChildhood emotional abuseCocaine treatment outcomesCocaine-dependent menCocaine-dependent adultsCocaine relapseAssociation of severityRisk of relapseSexual abusePhysical abuseGender-specific effectsInitial relapseDay cocaineCocaine dependenceDependent adultsInpatient SampleInpatient treatmentTreatment outcomesGreater severityAbuseDependent men
2005
A gender specific psychometric analysis of the early trauma inventory short form in cocaine dependent adults
Hyman SM, Garcia M, Kemp K, Mazure CM, Sinha R. A gender specific psychometric analysis of the early trauma inventory short form in cocaine dependent adults. Addictive Behaviors 2005, 30: 847-852. PMID: 15833587, PMCID: PMC2444015, DOI: 10.1016/j.addbeh.2004.08.009.Peer-Reviewed Original ResearchConceptsLifetime diagnosisDSM-IV Axis I DisordersMajor depressive disorderStructured Clinical InterviewAxis I DisordersCocaine-dependent adultsAlcohol use disorderCocaine-dependent menShort formChildhood Trauma Questionnaire-Short FormEarly traumaQuestionnaire-Short FormInternal consistencyClinical research toolDepressive disorderI disordersPredictive validityGood internal consistencyPsychiatric disordersUse disordersClinical InterviewDependent menCTQ-SFDependent adultsWomenThe Mediational Role of Relationship Efficacy and Resource Utilization in the Link Between Physical and Psychological Abuse and Relationship Termination
Raghavan C, Swan SC, Snow DL, Mazure CM. The Mediational Role of Relationship Efficacy and Resource Utilization in the Link Between Physical and Psychological Abuse and Relationship Termination. Violence Against Women 2005, 11: 65-88. PMID: 16043541, DOI: 10.1177/1077801204271514.Peer-Reviewed Original Research
2004
Gender effects of reported in utero tobacco exposure on smoking initiation, progression and nicotine dependence in adult offspring
Oncken C, McKee S, Krishnan-Sarin S, O'Malley S, Mazure C. Gender effects of reported in utero tobacco exposure on smoking initiation, progression and nicotine dependence in adult offspring. Nicotine & Tobacco Research 2004, 6: 829-833. PMID: 15700918, DOI: 10.1080/1462220042000282555.Peer-Reviewed Original ResearchConceptsUtero tobacco exposureTobacco exposureNicotine dependenceCigarette useUtero exposureAdult treatment-seeking smokersDaily cigarette useTreatment-seeking smokersCurrent cigarette useAdult smokersInteraction of exposureAdult offspringTobacco experimentationUnexposed malesCigarette experimentationProgressionSmokersExposureDaily useAgeGenderMalesOpposite effectFemalesGender effectsChildhood maltreatment as a risk factor for adult cardiovascular disease and depression.
Batten SV, Aslan M, Maciejewski PK, Mazure CM. Childhood maltreatment as a risk factor for adult cardiovascular disease and depression. The Journal Of Clinical Psychiatry 2004, 65: 249-54. PMID: 15003081, DOI: 10.4088/jcp.v65n0217.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseRisk factorsChildhood maltreatmentAdult depressionMultiple logistic regression modelAdult cardiovascular diseasePotent risk factorEffective clinical assessmentNational Comorbidity SurveySignificant increaseU.S. National Comorbidity SurveyLogistic regression modelsSex differencesCardiovascular eventsRepresentative sampleClinical assessmentLifetime depressionDiseaseAdult HealthPhysical outcomesWomenDepressionChildhood abuseMenDemographic factors
2000
Development and preliminary psychometric properties of an instrument for the measurement of childhood trauma: The early trauma inventory
Bremner J, Vermetten E, Mazure C. Development and preliminary psychometric properties of an instrument for the measurement of childhood trauma: The early trauma inventory. Depression And Anxiety 2000, 12: 1-12. PMID: 10999240, DOI: 10.1002/1520-6394(2000)12:1<1::aid-da1>3.0.co;2-w.Peer-Reviewed Original ResearchMeSH KeywordsAdultCase-Control StudiesChildChild AbuseDepressionFemaleHumansMaleMental DisordersMiddle AgedObserver VariationOdds RatioPanic DisorderPredictive Value of TestsPsychiatric Status Rating ScalesPsychometricsReproducibility of ResultsSchizophreniaStress Disorders, Post-TraumaticTrauma Severity IndicesConceptsEarly Trauma InventoryAbuse/traumaPreliminary psychometric propertiesChildhood traumaTrauma InventoryTraumatic experiencesPsychometric propertiesEarly traumatic experiencesAssessment of traumaGood convergent validityValid instrumentAcceptable inter-rater reliabilityTest-retest reliabilityMeasurement of symptomsSexual abuseConvergent validityComparison subjectsInternal consistencyPTSDInter-rater reliabilityAbuseInventoryTraumaValidityExperience
1999
Childhood Sexual Abuse as a Risk Factor for Depression in Women: Psychosocial and Neurobiological Correlates
Weiss EL, Longhurst JG, Mazure CM. Childhood Sexual Abuse as a Risk Factor for Depression in Women: Psychosocial and Neurobiological Correlates. American Journal Of Psychiatry 1999, 156: 816-828. PMID: 10360118, DOI: 10.1176/ajp.156.6.816.Peer-Reviewed Original ResearchConceptsAdult-onset depressionChildhood sexual abuseEarly stressorsHPA axisSexual abuseAdrenal axis functionLong-term dysregulationMajor depressive disorderStress-induced dysregulationDepressive illnessAxis functionDepressed patientsDepressive disorderRisk factorsLong-term effectsHuman studiesManual searchNeurobiological correlatesPsychosocial mechanismsDepressionWomenEarly stressDysregulationSubsequent developmentDysregulation results
1997
Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report
Bremner J, Randall P, Vermetten E, Staib L, Bronen R, Mazure C, Capelli S, McCarthy G, Innis R, Charney D. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report. Biological Psychiatry 1997, 41: 23-32. PMID: 8988792, PMCID: PMC3229101, DOI: 10.1016/s0006-3223(96)00162-x.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderLeft hippocampal volumeHippocampal volumeChildhood abuseAdult survivorsSmaller left hippocampal volumeAbuse-related posttraumatic stress disorderStress disorderSmaller hippocampal volumesCombat-related posttraumatic stress disorderMagnetic resonance imagingShort-term memoryHealthy subjectsYears of educationAlcohol abuseMagnetic resonance imaging-based measurementsComparison subjectsPTSD patientsImaging-based measurementsResonance imagingPatientsSexual abusePreliminary reportSurvivorsComparison region