2004
Combining norepinephrine and serotonin reuptake inhibition mechanisms for treatment of depression: a double-blind, randomized study
Nelson JC, Mazure CM, Jatlow PI, Bowers MB, Price LH. Combining norepinephrine and serotonin reuptake inhibition mechanisms for treatment of depression: a double-blind, randomized study. Biological Psychiatry 2004, 55: 296-300. PMID: 14744472, DOI: 10.1016/j.biopsych.2003.08.007.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic Uptake InhibitorsAdultAntidepressive Agents, Second-GenerationAntidepressive Agents, TricyclicChromatography, High Pressure LiquidDepressive DisorderDesipramineDouble-Blind MethodDrug Therapy, CombinationFemaleFluoxetineHumansMaleMiddle AgedNorepinephrinePsychiatric Status Rating ScalesSelective Serotonin Reuptake InhibitorsSerotoninTreatment OutcomeConceptsMontgomery-Asberg Depression Rating ScaleHamilton Depression Rating Scale scoresDepression Rating Scale scoresNonpsychotic unipolar major depressionPatient withdrew consentTreatment-resistant patientsWeeks of hospitalizationWeeks of treatmentCombination of fluoxetineOnset of actionAdequate plasma levelsDouble-blind conditionsDepression Rating ScaleTreatment of depressionRating Scale scoresUnipolar major depressionDrug plasma concentrationsDMI doseWithdrew consentAntidepressant medicationRandomized studyReuptake inhibitionSerotonergic agentsPlasma levelsMajor depression
2002
Plasma catecholamine metabolites in antidepressant-exacerbated mania and psychosis
Fortunati F, Mazure C, Preda A, Wahl R, Bowers M. Plasma catecholamine metabolites in antidepressant-exacerbated mania and psychosis. Journal Of Affective Disorders 2002, 68: 331-334. PMID: 12063160, DOI: 10.1016/s0165-0327(00)00327-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntidepressive AgentsBipolar DisorderCatecholaminesComorbidityFemaleHomovanillic AcidHumansMaleMiddle AgedPsychoses, Substance-InducedRisk FactorsSelective Serotonin Reuptake Inhibitors
2001
Antidepressant-associated mania and psychosis resulting in psychiatric admissions.
Preda A, MacLean RW, Mazure CM, Bowers MB. Antidepressant-associated mania and psychosis resulting in psychiatric admissions. The Journal Of Clinical Psychiatry 2001, 62: 30-3. PMID: 11235925, DOI: 10.4088/jcp.v62n0107.Peer-Reviewed Original ResearchConceptsSelective serotonin reuptake inhibitorsGeneral hospital psychiatric unitAntidepressant-associated maniaNewer atypical agentsSide effect profileSerotonin reuptake inhibitorsHospital psychiatric unitRate of admissionAdverse behavioral effectsAntidepressant useReuptake inhibitorsEffect profileAtypical agentsPsychiatric admissionsAntidepressant drugsPsychiatric unitBehavioral effectsAdverse behavioral reactionsAdmissionSignificant increasePsychosisManiaDrugsTolerabilityAntidepressants