2017
Gender differences in the real-world effectiveness of smoking cessation medications: Findings from the 2010–2011 Tobacco Use Supplement to the Current Population Survey
Smith PH, Zhang J, Weinberger AH, Mazure CM, McKee SA. Gender differences in the real-world effectiveness of smoking cessation medications: Findings from the 2010–2011 Tobacco Use Supplement to the Current Population Survey. Drug And Alcohol Dependence 2017, 178: 485-491. PMID: 28715776, PMCID: PMC6779031, DOI: 10.1016/j.drugalcdep.2017.05.046.Peer-Reviewed Original ResearchConceptsTransdermal nicotine patchUnassisted quit attemptsClinical trial dataTobacco Use SupplementQuit attemptsTrial dataClinical trial findingsReal-world effectivenessSample of smokersGender differencesRelevant gender differencesCessation optionsCessation medicationsCessation pharmacotherapyNicotine patchMedication interactionsSmoking cessationPotential confoundersTrial findingsVareniclineComparative effectivenessPropensity scoreCross-sectional dataWomenMedications
2016
Sex Differences in Smoking Cessation Pharmacotherapy Comparative Efficacy: A Network Meta-analysis
Smith PH, Weinberger AH, Zhang J, Emme E, Mazure CM, McKee SA. Sex Differences in Smoking Cessation Pharmacotherapy Comparative Efficacy: A Network Meta-analysis. Nicotine & Tobacco Research 2016, 19: 273-281. PMID: 27613893, PMCID: PMC5939704, DOI: 10.1093/ntr/ntw144.Peer-Reviewed Original ResearchConceptsTransdermal nicotineSmoking cessationBupropion SRComparative efficacyFirst option treatmentSustained release bupropionPlacebo-controlled trialSex differencesCigarette smoking cessationNetwork Meta-AnalysisRelease bupropionCessation pharmacotherapyOption treatmentGeneral community sampleCigarette smokersQuit ratesVarenicline's efficacyPharmacological interventionsVareniclineBupropionNicotine addictionMeta-AnalysisPlaceboSimilar outcomesSignificant sex differences
2015
Sex Differences in Varenicline Efficacy for Smoking Cessation: A Meta-Analysis
McKee SA, Smith PH, Kaufman M, Mazure CM, Weinberger AH. Sex Differences in Varenicline Efficacy for Smoking Cessation: A Meta-Analysis. Nicotine & Tobacco Research 2015, 18: 1002-1011. PMID: 26446070, PMCID: PMC5942618, DOI: 10.1093/ntr/ntv207.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleHumansMaleNicotinic AgonistsRandomized Controlled Trials as TopicSex FactorsSmoking CessationSmoking PreventionVareniclineConceptsSmoking cessation medicationsCessation medicationsSmoking cessationDouble-blind placebo-controlled trialEfficacy of vareniclinePlacebo-controlled trialShort-term outcomesClinical trial dataSex differencesSimilar ratesWeek 52Week 24Women smokersNicotine replacementWeek 12Outcome endpointsTherapeutic responseClinical trialsContinuous abstinenceVarenicline's efficacyVareniclinePlacebo outcomesEqual efficacySex disparitiesEffective FDATargeting the Noradrenergic System for Gender-Sensitive Medication Development for Tobacco Dependence
Verplaetse TL, Weinberger AH, Smith PH, Cosgrove KP, Mineur YS, Picciotto MR, Mazure CM, McKee SA. Targeting the Noradrenergic System for Gender-Sensitive Medication Development for Tobacco Dependence. Nicotine & Tobacco Research 2015, 17: 486-495. PMID: 25762760, PMCID: PMC4432402, DOI: 10.1093/ntr/ntu280.Peer-Reviewed Original ResearchMeSH KeywordsFemaleGender IdentityHumansMaleNicotineReceptors, AndrogenSmoking CessationSmoking PreventionSubstance Withdrawal SyndromeConceptsSmoking cessationNoradrenergic systemClinical evidenceTobacco dependenceNoradrenergic activityMedication developmentPoor smoking cessation outcomesCause of morbiditySmoking cessation outcomesStress reactivitySex-specific mechanismsLower quit ratesNicotine-related reinforcementCurrent medicationsMedication effectivenessNicotine reinforcementCessation outcomesNoradrenergic agentsQuit ratesTreatment strategiesTobacco useNoradrenergic compoundsSmoking outcomesTreatment developmentWomenSystematic and Meta-Analytic Review of Research Examining the Impact of Menstrual Cycle Phase and Ovarian Hormones on Smoking and Cessation
Weinberger AH, Smith PH, Allen SS, Cosgrove KP, Saladin ME, Gray KM, Mazure CM, Wetherington CL, McKee SA. Systematic and Meta-Analytic Review of Research Examining the Impact of Menstrual Cycle Phase and Ovarian Hormones on Smoking and Cessation. Nicotine & Tobacco Research 2015, 17: 407-421. PMID: 25762750, PMCID: PMC4429881, DOI: 10.1093/ntr/ntu249.Peer-Reviewed Original ResearchConceptsMenstrual cycle phaseHormone levelsOvarian hormonesLuteal phaseSmoking behaviorSearch termsOvarian hormone levelsMenstrual phase effectsCessation-related behaviorsTiming of interventionNegative subjective effectsMenstrual cycle effectsProgesterone administrationFollicular phaseMedication responseQuit ratesTonic cravingInclusion criteriaMenstrual phaseNonsignificant trendSmoking outcomesCycle phaseSmokingSystematic reviewGreater tonic
2014
Smoking and mental illness in the US population
Smith PH, Mazure CM, McKee SA. Smoking and mental illness in the US population. Tobacco Control 2014, 23: e147. PMID: 24727731, PMCID: PMC4201650, DOI: 10.1136/tobaccocontrol-2013-051466.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCross-Sectional StudiesDiagnostic and Statistical Manual of Mental DisordersFemaleHealth Status DisparitiesHumansLongitudinal StudiesMaleMental DisordersMental Health ServicesMiddle AgedPrevalenceSmokingSmoking CessationSocioeconomic FactorsTobacco Use DisorderYoung AdultConceptsPsychiatric diagnosisCessation ratesQuit ratesSpecific diagnosisMental health service useEstimates of smokingHealth service useCurrent psychiatric diagnosisSpecific psychiatric diagnosesNational Epidemiologic SurveyTimes greater oddsPast-year psychiatric diagnosisHeavy smokingPsychiatric comorbiditySmoking ratesTobacco useTreatment useComorbid disordersSmokingGreater prevalenceService useEpidemiologic SurveyGreater oddsCohort surveyUS population
2013
Changes in Smoking for Adults with and without Alcohol and Drug Use Disorders: Longitudinal Evaluation in the US Population
Weinberger AH, Pilver CE, Hoff RA, Mazure CM, McKee SA. Changes in Smoking for Adults with and without Alcohol and Drug Use Disorders: Longitudinal Evaluation in the US Population. The American Journal Of Drug And Alcohol Abuse 2013, 39: 186-193. PMID: 23721534, PMCID: PMC3696891, DOI: 10.3109/00952990.2013.785557.Peer-Reviewed Original ResearchConceptsCurrent drug use disordersDrug use disordersCurrent alcohol use disorderAlcohol use disorderDUD diagnosesUse disordersSmoking cessationDaily smokersSmoking relapsePast alcohol use disordersFormer daily smokersCurrent daily smokersUS adult populationDaily cigarette smokersAssessment 3 yearsNational Epidemiologic SurveyWave 2Gender-specific effectsCigarette smokersEpidemiologic SurveyDiagnosis interactionRelapse behaviorSmokingUS populationAdult population
2012
Two Decades of Smoking Cessation Treatment Research on Smokers with Depression: 1990–2010
Weinberger AH, Mazure CM, Morlett A, McKee SA. Two Decades of Smoking Cessation Treatment Research on Smokers with Depression: 1990–2010. Nicotine & Tobacco Research 2012, 15: 1014-1031. PMID: 23100459, PMCID: PMC3693502, DOI: 10.1093/ntr/nts213.Peer-Reviewed Original ResearchConceptsRelationship of depressionSmoking cessation outcomesCessation outcomesSmoking cessationTreatment outcomesCurrent major depressive disorderMajor depressive disorderCurrent depression symptomsClinical trialsDepressive disorderMinor depressionMajor depressionInclusion criteriaMEDLINE searchPast diagnosisTreatment approachesDepression symptomsHealth-related risksMajority of studiesPotential articlesDepressionRacial differencesOutcomesCessationSmokersThe relationship of dysthymia, minor depression, and gender to changes in smoking for current and former smokers: Longitudinal evaluation in the U.S. population
Weinberger AH, Pilver CE, Desai RA, Mazure CM, McKee SA. The relationship of dysthymia, minor depression, and gender to changes in smoking for current and former smokers: Longitudinal evaluation in the U.S. population. Drug And Alcohol Dependence 2012, 127: 170-176. PMID: 22809897, PMCID: PMC3480998, DOI: 10.1016/j.drugalcdep.2012.06.028.Peer-Reviewed Original ResearchConceptsFormer daily smokersCurrent daily smokersCurrent dysthymiaMinor depressionLifetime dysthymiaDaily smokersFormer smokersSmoking behaviorDaily cigarette smokersNational Epidemiologic SurveyWave 2Gender-specific effectsCigarette smokersSmoking abstinenceMajor depressionSmokersEpidemiologic SurveyDysthymiaDiagnosis interactionRespective diagnosisDecreased likelihoodLongitudinal evaluationRelated conditionsSmokingDepressionThe relationship of major depressive disorder and gender to changes in smoking for current and former smokers: longitudinal evaluation in the US population
Weinberger AH, Pilver CE, Desai RA, Mazure CM, McKee SA. The relationship of major depressive disorder and gender to changes in smoking for current and former smokers: longitudinal evaluation in the US population. Addiction 2012, 107: 1847-1856. PMID: 22429388, PMCID: PMC3419319, DOI: 10.1111/j.1360-0443.2012.03889.x.Peer-Reviewed Original ResearchConceptsCurrent major depressive disorderMajor depressive disorderFormer daily smokersDepressive disorderFormer smokersNational Epidemiologic SurveyDaily smokersWave 2Current daily smokersUnited States civilianWave 1Smoking statusNicotine dependenceSmoking relapseAlcohol abuseSmokersEpidemiologic SurveyDiagnosis interactionRespective diagnosisUS populationLongitudinal evaluationRelated conditionsSmokingLower likelihoodDistrict of Columbia
2010
Menstrual cycle phase at quit date and smoking abstinence at 6 weeks in an open label trial of bupropion
Mazure CM, Toll B, McKee SA, Wu R, O’Malley S. Menstrual cycle phase at quit date and smoking abstinence at 6 weeks in an open label trial of bupropion. Drug And Alcohol Dependence 2010, 114: 68-72. PMID: 20832955, PMCID: PMC3016455, DOI: 10.1016/j.drugalcdep.2010.07.024.Peer-Reviewed Original ResearchMeSH KeywordsAdultBupropionFemaleFollicular PhaseHumansLuteal PhaseMenstrual CycleSmokingSmoking CessationTime FactorsTreatment OutcomeConceptsMenstrual cycle phaseQuit datePoint prevalence abstinencePremenopausal womenBupropion SRFollicular phaseLuteal phaseAbsence of pharmacotherapySustained release bupropionOpen-label trialCycle phaseMechanism of actionRelease bupropionLabel trialNicotine replacementCessation interventionsOpen trialTreatment completionCessation outcomesContinuous abstinenceQuit dayGonadal hormonesTreatment periodAbstinence outcomesQuit attemptsExploring the impact of gender and reproductive status on outcomes in a randomized clinical trial of naltrexone augmentation of nicotine patch
Epperson CN, Toll B, Wu R, Amin Z, Czarkowski KA, Jatlow P, Mazure CM, O’Malley S. Exploring the impact of gender and reproductive status on outcomes in a randomized clinical trial of naltrexone augmentation of nicotine patch. Drug And Alcohol Dependence 2010, 112: 1-8. PMID: 20561758, PMCID: PMC2946976, DOI: 10.1016/j.drugalcdep.2010.04.021.Peer-Reviewed Original ResearchConceptsPlacebo groupStudy completersNaltrexone doseClinical trialsContinuous abstinenceOral naltrexone treatmentNicotine patch therapyNicotine replacement therapyInteractive voice responseRandomized clinical trialsMenstrual cycle statusEffect of doseNaltrexone augmentationNaltrexone groupAdverse eventsNaltrexone treatmentNicotine patchPatch therapyReplacement therapyQuit dayWeek 1AbstinenceDoseWomenLess adherent
2009
Gender Differences in Associations between Lifetime Alcohol, Depression, Panic Disorder, and Posttraumatic Stress Disorder and Tobacco Withdrawal
Weinberger AH, Maciejewski PK, McKee SA, Reutenauer EL, Mazure CM. Gender Differences in Associations between Lifetime Alcohol, Depression, Panic Disorder, and Posttraumatic Stress Disorder and Tobacco Withdrawal. American Journal On Addictions 2009, 18: 140-147. PMID: 19283566, PMCID: PMC2874459, DOI: 10.1080/10550490802544888.Peer-Reviewed Original ResearchConceptsAlcohol abuse/dependenceAbuse/dependenceMajor depressionWithdrawal symptomsPsychiatric statusSmoking relapsePanic disorderIndices of withdrawalStrong associationSmoking cessation interventionNational Comorbidity SurveyPosttraumatic stress disorderGender-specific effectsCessation interventionsNicotine withdrawalTobacco withdrawalRetrospective dataStress disorderLifetime alcoholLonger durationDepressionWithdrawalDisordersRelapseMultiple regression analysisThe Inclusion of Women and Minorities in Smoking Cessation Clinical Trials: A Systematic Review
Dickerson DL, Leeman RF, Mazure CM, O'Malley SS. The Inclusion of Women and Minorities in Smoking Cessation Clinical Trials: A Systematic Review. American Journal On Addictions 2009, 18: 21-28. PMID: 19219662, PMCID: PMC2764011, DOI: 10.1080/10550490802408522.Peer-Reviewed Original Research
2008
Relationship of perceived risks of smoking cessation to symptoms of withdrawal, craving, and depression during short-term smoking abstinence
Weinberger AH, Krishnan-Sarin S, Mazure CM, McKee SA. Relationship of perceived risks of smoking cessation to symptoms of withdrawal, craving, and depression during short-term smoking abstinence. Addictive Behaviors 2008, 33: 960-963. PMID: 18384974, PMCID: PMC2442160, DOI: 10.1016/j.addbeh.2008.02.013.Peer-Reviewed Original ResearchConceptsShort-term smoking abstinenceShort-term abstinenceSelf-reported experiencesExperienced withdrawal symptomsWithdrawal symptomsBehavioral interventionsSmoking cessationContingency managementCravingRisk beliefsSmoking abstinenceDaily smokersHigh levelsRelationship of riskRisk perceptionNicotine dependenceAbstinenceParticipantsCurrent studySymptoms of withdrawalDepressionBaseline smokingRisk groupsSymptomsRelationshipMessage Framing for Smoking Cessation: The Interaction of Risk Perceptions and Gender
Toll BA, Salovey P, O'Malley SS, Mazure CM, Latimer A, McKee SA. Message Framing for Smoking Cessation: The Interaction of Risk Perceptions and Gender. Nicotine & Tobacco Research 2008, 10: 195-200. PMID: 18188760, PMCID: PMC2527723, DOI: 10.1080/14622200701767803.Peer-Reviewed Original ResearchConceptsMessage framing interventionsRisk of cessationSmoking cessationLung cancerClinical trialsGain-framed messagesHigh riskSmoking relapseHealth message framingHealth problemsLoss-framed messagesSmokingFraming interventionCessationNumber of daysInfluence of genderInterventionRiskRisk perceptionWomenMedian splitGain-framed conditionDaysMenGender differences
2005
Knowledge and perceived risk of smoking-related conditions: a survey of cigarette smokers
Oncken C, McKee S, Krishnan-Sarin S, O'Malley S, Mazure CM. Knowledge and perceived risk of smoking-related conditions: a survey of cigarette smokers. Preventive Medicine 2005, 40: 779-784. PMID: 15850879, DOI: 10.1016/j.ypmed.2004.09.024.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsChi-Square DistributionConnecticutCross-Sectional StudiesFemaleFollow-Up StudiesHealth Knowledge, Attitudes, PracticeHumansIncidenceMaleMiddle AgedPredictive Value of TestsProbabilityRisk AssessmentRisk-TakingSex FactorsSmokingSmoking CessationSmoking PreventionSurveys and QuestionnairesSurvival RateTobacco Use DisorderConceptsSmoking-related conditionsMedical conditionsSmoking-related disease riskDisease categoriesPremature deathOral health diseasesSmoking-related cancersSmoking-related illnessesAdult treatment-seeking smokersPersonal health risksQuality of lifeTreatment-seeking smokersCurrent smokersCigarette smokersLung cancerOral diseasesSmokersSmokingDisease riskReproductive risksHealth diseasesCancerRiskHealth risksDiseasePerceived risks and benefits of smoking cessation: Gender-specific predictors of motivation and treatment outcome
McKee SA, O'Malley SS, Salovey P, Krishnan-Sarin S, Mazure CM. Perceived risks and benefits of smoking cessation: Gender-specific predictors of motivation and treatment outcome. Addictive Behaviors 2005, 30: 423-435. PMID: 15718060, DOI: 10.1016/j.addbeh.2004.05.027.Peer-Reviewed Original ResearchConceptsPretreatment motivationTreatment-seeking smokersSelf-report instrumentGood psychometric propertiesSmoking cessationGender-specific predictorsTreatment outcomesSmoking cessation trialLikelihood ratingsBehavioral intentionsPsychometric propertiesMotivationIntervention strategiesCessation trialGender differencesPublic education campaignsPrimary aimStrong associationBeliefsParticipantsRatingsIntentionOutcomesSubsampleEducation campaigns
2004
Gender effects of reported in utero tobacco exposure on smoking initiation, progression and nicotine dependence in adult offspring
Oncken C, McKee S, Krishnan-Sarin S, O'Malley S, Mazure C. Gender effects of reported in utero tobacco exposure on smoking initiation, progression and nicotine dependence in adult offspring. Nicotine & Tobacco Research 2004, 6: 829-833. PMID: 15700918, DOI: 10.1080/1462220042000282555.Peer-Reviewed Original ResearchConceptsUtero tobacco exposureTobacco exposureNicotine dependenceCigarette useUtero exposureAdult treatment-seeking smokersDaily cigarette useTreatment-seeking smokersCurrent cigarette useAdult smokersInteraction of exposureAdult offspringTobacco experimentationUnexposed malesCigarette experimentationProgressionSmokersExposureDaily useAgeGenderMalesOpposite effectFemalesGender effects
2003
Sex differences in the effects of stressful life events on changes in smoking status
McKee SA, Maciejewski PK, Falba T, Mazure CM. Sex differences in the effects of stressful life events on changes in smoking status. Addiction 2003, 98: 847-855. PMID: 12780373, DOI: 10.1046/j.1360-0443.2003.00408.x.Peer-Reviewed Original ResearchConceptsStressful life eventsLife eventsSmoking statusAdverse financial eventsCurrent smokersHealth eventsCommunity-based sampleOccurrence of relapseImportant risk factorAdverse health eventsSubstance useFormer smokersFinancial eventsRisk factorsLogistic regression proceduresOdds ratioTobacco useAmericans' ChangingInteractive effectsSex differencesSmokersGreater deleterious effectWomenAbstinenceSmoking