2023
Considerations of Sex and Gender in FDA Tobacco Regulation
Davis D, Krishnan-Sarin S, Mazure C. Considerations of Sex and Gender in FDA Tobacco Regulation. JAMA 2023, 329: 2017-2018. PMID: 37233997, PMCID: PMC11094658, DOI: 10.1001/jama.2023.6803.Peer-Reviewed Original ResearchPre- and peri-traumatic event stressors drive gender differences in chronic stress-related psychological sequelae: A prospective cohort study of COVID-19 frontline healthcare providers
Hennein R, Lowe S, Feingold J, Feder A, Peccoralo L, Ripp J, Mazure C, Pietrzak R. Pre- and peri-traumatic event stressors drive gender differences in chronic stress-related psychological sequelae: A prospective cohort study of COVID-19 frontline healthcare providers. Journal Of Psychiatric Research 2023, 162: 88-94. PMID: 37105023, DOI: 10.1016/j.jpsychires.2023.04.009.Peer-Reviewed Original ResearchConceptsMajor depressive disorderPosttraumatic stress disorderProspective cohort studyHealthcare providersCohort studyLarge tertiary care hospitalPsychological sequelaeSymptoms of MDDMental health risk factorsTertiary care hospitalProbable major depressive disorderWomen's healthcare providersHealth risk factorsFrontline healthcare providersCare hospitalRisk factorsDepressive disorderGender differencesStress disorderAnxiety disordersWomenSequelaeCOVID-19DisordersCOVID-19 pandemic
2022
Precision medicine requires understanding how both sex and gender influence health
Stachenfeld NS, Mazure CM. Precision medicine requires understanding how both sex and gender influence health. Cell 2022, 185: 1619-1622. PMID: 35561661, DOI: 10.1016/j.cell.2022.04.012.Peer-Reviewed Original Research
2021
Are Women Less Psychologically Resilient Than Men? Background Stressors Underlying Gender Differences in Reports of Stress-Related Psychological Sequelae.
Lowe SR, Hennein R, Feingold JH, Peccoralo LA, Ripp JA, Mazure CM, Pietrzak RH. Are Women Less Psychologically Resilient Than Men? Background Stressors Underlying Gender Differences in Reports of Stress-Related Psychological Sequelae. The Journal Of Clinical Psychiatry 2021, 83 PMID: 34936244, DOI: 10.4088/jcp.21br14098.Peer-Reviewed Original ResearchThis is Your Brain in Meltdown
Arnsten A, Mazure CM, Sinha R. This is Your Brain in Meltdown. Scientific American 2021, 306: 48-53. PMID: 22486116, PMCID: PMC4774859, DOI: 10.1038/scientificamerican0412-48.Peer-Reviewed Original ResearchWomen, opioid use and addiction
Goetz TG, Becker JB, Mazure CM. Women, opioid use and addiction. The FASEB Journal 2021, 35: e21303. PMID: 33433026, DOI: 10.1096/fj.202002125r.Peer-Reviewed Original ResearchConceptsOpioid useChronic painPrescription opioidsEffective public health policiesOngoing opioid epidemicPublic health policyComparison of womenWidespread prescribingOpioid medicationsPublic health crisisOpioid epidemicOpioid addictionOpioidsTreatment opportunitiesTreatment approachesSynthetic opioidsMedicationsPainPsychosocial effectsHealth policyWomen's exposureWomenCurrent coronavirus pandemicHealth crisisMen
2018
Women and opioids: something different is happening here
Mazure CM, Fiellin DA. Women and opioids: something different is happening here. The Lancet 2018, 392: 9-11. PMID: 30047402, DOI: 10.1016/s0140-6736(18)31203-0.Peer-Reviewed Original Research
2017
Trajectories of depressive and anxiety symptoms in older adults: a 6‐year prospective cohort study
Holmes SE, Esterlis I, Mazure CM, Lim YY, Ames D, Rainey‐Smith S, Fowler C, Ellis K, Martins RN, Salvado O, Doré V, Villemagne VL, Rowe CC, Laws SM, Masters CL, Pietrzak RH, Maruff P, Imaging B. Trajectories of depressive and anxiety symptoms in older adults: a 6‐year prospective cohort study. International Journal Of Geriatric Psychiatry 2017, 33: 405-413. PMID: 28736899, PMCID: PMC5773367, DOI: 10.1002/gps.4761.Peer-Reviewed Original ResearchMeSH KeywordsAgedAllelesAlzheimer DiseaseAnxiety DisordersApolipoprotein E4AttentionBrain-Derived Neurotrophic FactorCognitionDepressive DisorderDisease ProgressionExecutive FunctionFemaleHumansLogistic ModelsMaleMiddle AgedPositron-Emission TomographyProspective StudiesQuality of LifeRisk FactorsSex FactorsConceptsOlder adultsAnxiety symptomsPredominant trajectoriesRisk factorsLatent growth mixture modelingAlzheimer's diseaseApolipoprotein epsilon 4 alleleSex-specific risk factorsLower attentional functionBinary logistic regression analysisEpsilon 4 alleleElevated depressive symptomsGrowth mixture modelingLogistic regression analysisQuality of lifePositron emission tomographyNormal older adultsSubthreshold depressiveMale sexBaseline predictorsDepressive symptomsVal66Met alleleClinical depressionLower executive functionAnxiety trajectoriesGender differences in the real-world effectiveness of smoking cessation medications: Findings from the 2010–2011 Tobacco Use Supplement to the Current Population Survey
Smith PH, Zhang J, Weinberger AH, Mazure CM, McKee SA. Gender differences in the real-world effectiveness of smoking cessation medications: Findings from the 2010–2011 Tobacco Use Supplement to the Current Population Survey. Drug And Alcohol Dependence 2017, 178: 485-491. PMID: 28715776, PMCID: PMC6779031, DOI: 10.1016/j.drugalcdep.2017.05.046.Peer-Reviewed Original ResearchConceptsTransdermal nicotine patchUnassisted quit attemptsClinical trial dataTobacco Use SupplementQuit attemptsTrial dataClinical trial findingsReal-world effectivenessSample of smokersGender differencesRelevant gender differencesCessation optionsCessation medicationsCessation pharmacotherapyNicotine patchMedication interactionsSmoking cessationPotential confoundersTrial findingsVareniclineComparative effectivenessPropensity scoreCross-sectional dataWomenMedicationsDifferential Associations Between Excess Body Weight and Psychiatric Disorders in Men and Women
Husky MM, Mazure CM, Ruffault A, Flahault C, Kovess-Masfety V. Differential Associations Between Excess Body Weight and Psychiatric Disorders in Men and Women. Journal Of Women's Health 2017, 27: 183-190. PMID: 28686068, DOI: 10.1089/jwh.2016.6248.Peer-Reviewed Original ResearchConceptsExcess body weightExcess weightPsychiatric disordersBody weightMajor depressionWeight statusFirst large-scale population-based studyComposite International Diagnostic Interview Short FormLarge-scale population-based studyCo-occurring psychiatric disordersPast-year psychiatric disordersBody mass indexPopulation-based studyRates of obesityCommon psychiatric disordersExcess weight statusCross-sectional general population surveyGeneral population surveyNormal weightMass indexObsessive-compulsive disorderPsychiatric assessmentPanic disorderObesityPsychiatric conditions
2016
Investigating Veterans’ Pre-, Peri-, and Post-Deployment Experiences as Potential Risk Factors for Problem Gambling
Whiting SW, Potenza MN, Park CL, McKee SA, Mazure CM, Hoff RA. Investigating Veterans’ Pre-, Peri-, and Post-Deployment Experiences as Potential Risk Factors for Problem Gambling. Journal Of Behavioral Addictions 2016, 5: 213-220. PMID: 27156377, PMCID: PMC5387772, DOI: 10.1556/2006.5.2016.027.Peer-Reviewed Original Research
2015
Sex Differences in Varenicline Efficacy for Smoking Cessation: A Meta-Analysis
McKee SA, Smith PH, Kaufman M, Mazure CM, Weinberger AH. Sex Differences in Varenicline Efficacy for Smoking Cessation: A Meta-Analysis. Nicotine & Tobacco Research 2015, 18: 1002-1011. PMID: 26446070, PMCID: PMC5942618, DOI: 10.1093/ntr/ntv207.Peer-Reviewed Original ResearchConceptsSmoking cessation medicationsCessation medicationsSmoking cessationDouble-blind placebo-controlled trialEfficacy of vareniclinePlacebo-controlled trialShort-term outcomesClinical trial dataSex differencesSimilar ratesWeek 52Week 24Women smokersNicotine replacementWeek 12Outcome endpointsTherapeutic responseClinical trialsContinuous abstinenceVarenicline's efficacyVareniclinePlacebo outcomesEqual efficacySex disparitiesEffective FDAImpact of Exposure to Childhood Maltreatment on Transitions to Alcohol Dependence in Women and Men
Oberleitner LM, Smith PH, Weinberger AH, Mazure CM, McKee SA. Impact of Exposure to Childhood Maltreatment on Transitions to Alcohol Dependence in Women and Men. Child Maltreatment 2015, 20: 301-308. PMID: 26130105, PMCID: PMC4868049, DOI: 10.1177/1077559515591270.Peer-Reviewed Original ResearchConceptsAlcohol useChildhood maltreatmentAlcohol dependenceFourth Edition alcohol dependencePoisson regression analysisNational Epidemiologic SurveyNegative alcohol-related outcomesProblematic alcohol useImpact of exposureEpidemiologic SurveyEarly interventionAlcohol-related outcomesMental disordersBehavioral treatmentRelated conditionsPrevention effortsStatistical ManualOutcome variablesAlcohol initiationWomenRegression analysisAgeMenFirst useMaltreatment
2014
Gender and Stress in Predicting Depressive Symptoms Following Stroke
Mazure CM, Weinberger AH, Pittman B, Sibon I, Swendsen J. Gender and Stress in Predicting Depressive Symptoms Following Stroke. Cerebrovascular Diseases 2014, 38: 240-246. PMID: 25401293, PMCID: PMC4283501, DOI: 10.1159/000365838.Peer-Reviewed Original ResearchConceptsPost-stroke depressionPost-stroke patientsDepressive symptomsStressful life eventsClinic visitsElectronic momentary assessmentRisk of PSDThree monthsLife eventsStandardized depression scalesRegular clinic visitsSpecific depressive symptomsStandard clinical assessmentPredicting Depressive SymptomsStroke centersAppetite changesProspective studyFunctional outcomeClinical assessmentDepression ScaleDepression assessmentGender differencesAmbulatory monitoringSignificant associationSymptoms
2012
Two Decades of Smoking Cessation Treatment Research on Smokers with Depression: 1990–2010
Weinberger AH, Mazure CM, Morlett A, McKee SA. Two Decades of Smoking Cessation Treatment Research on Smokers with Depression: 1990–2010. Nicotine & Tobacco Research 2012, 15: 1014-1031. PMID: 23100459, PMCID: PMC3693502, DOI: 10.1093/ntr/nts213.Peer-Reviewed Original ResearchConceptsRelationship of depressionSmoking cessation outcomesCessation outcomesSmoking cessationTreatment outcomesCurrent major depressive disorderMajor depressive disorderCurrent depression symptomsClinical trialsDepressive disorderMinor depressionMajor depressionInclusion criteriaMEDLINE searchPast diagnosisTreatment approachesDepression symptomsHealth-related risksMajority of studiesPotential articlesDepressionRacial differencesOutcomesCessationSmokersThe relationship of dysthymia, minor depression, and gender to changes in smoking for current and former smokers: Longitudinal evaluation in the U.S. population
Weinberger AH, Pilver CE, Desai RA, Mazure CM, McKee SA. The relationship of dysthymia, minor depression, and gender to changes in smoking for current and former smokers: Longitudinal evaluation in the U.S. population. Drug And Alcohol Dependence 2012, 127: 170-176. PMID: 22809897, PMCID: PMC3480998, DOI: 10.1016/j.drugalcdep.2012.06.028.Peer-Reviewed Original ResearchConceptsFormer daily smokersCurrent daily smokersCurrent dysthymiaMinor depressionLifetime dysthymiaDaily smokersFormer smokersSmoking behaviorDaily cigarette smokersNational Epidemiologic SurveyWave 2Gender-specific effectsCigarette smokersSmoking abstinenceMajor depressionSmokersEpidemiologic SurveyDysthymiaDiagnosis interactionRespective diagnosisDecreased likelihoodLongitudinal evaluationRelated conditionsSmokingDepression
2011
Corticostriatal-Limbic Gray Matter Morphology in Adolescents With Self-reported Exposure to Childhood Maltreatment
Edmiston EE, Wang F, Mazure CM, Guiney J, Sinha R, Mayes LC, Blumberg HP. Corticostriatal-Limbic Gray Matter Morphology in Adolescents With Self-reported Exposure to Childhood Maltreatment. JAMA Pediatrics 2011, 165: 1069-1077. PMID: 22147775, PMCID: PMC3607102, DOI: 10.1001/archpediatrics.2011.565.Peer-Reviewed Original ResearchInclusion of Gender in Emergency Medicine Research
Safdar B, McGregor AJ, McKee SA, Ali A, Radulescu R, Himelfarb NT, Klein MR, Mazure CM. Inclusion of Gender in Emergency Medicine Research. Academic Emergency Medicine 2011, 18: e1-e4. PMID: 21314767, DOI: 10.1111/j.1553-2712.2010.00978.x.Peer-Reviewed Original ResearchConceptsHealth outcomesEmergency departmentOdds ratioEmergency medicineConfidence intervalsEffect of genderPrimary hypothesisEmergency medical servicesGender-specific approachEmergency medicine researchAcute settingAdult human subjectsCardiovascular diseaseEmergency physiciansEmergency careManagement of diseasesStudy subjectsClinical specialistsPatient careStudy designStudy periodChi-squareMedical servicesOutcomesHuman subjects
2010
Inclusion of Women and Gender-Specific Analyses in Randomized Clinical Trials of Treatments for Depression
Weinberger AH, McKee SA, Mazure CM. Inclusion of Women and Gender-Specific Analyses in Randomized Clinical Trials of Treatments for Depression. Journal Of Women's Health 2010, 19: 1727-1732. PMID: 20799923, PMCID: PMC2936499, DOI: 10.1089/jwh.2009.1784.Peer-Reviewed Original ResearchConceptsRecent randomized clinical trialsRandomized clinical trialsClinical trialsGender-specific analysisDepression treatmentHealth (NIH) Revitalization ActCost of depressionInterventional studyInclusion of womenHigh prevalenceTreatment responseMEDLINE searchTreatment efficacyGender differencesPossible gender differencesDepression researchTrialsWomenDepressionNational InstituteRevitalization ActTreatmentFemale participantsOutcomesGender
2008
Relationship of perceived risks of smoking cessation to symptoms of withdrawal, craving, and depression during short-term smoking abstinence
Weinberger AH, Krishnan-Sarin S, Mazure CM, McKee SA. Relationship of perceived risks of smoking cessation to symptoms of withdrawal, craving, and depression during short-term smoking abstinence. Addictive Behaviors 2008, 33: 960-963. PMID: 18384974, PMCID: PMC2442160, DOI: 10.1016/j.addbeh.2008.02.013.Peer-Reviewed Original ResearchConceptsShort-term smoking abstinenceShort-term abstinenceSelf-reported experiencesExperienced withdrawal symptomsWithdrawal symptomsBehavioral interventionsSmoking cessationContingency managementCravingRisk beliefsSmoking abstinenceDaily smokersHigh levelsRelationship of riskRisk perceptionNicotine dependenceAbstinenceParticipantsCurrent studySymptoms of withdrawalDepressionBaseline smokingRisk groupsSymptomsRelationship