2016
Brain circuitry associated with the development of substance use in bipolar disorder and preliminary evidence for sexual dimorphism in adolescents
Lippard ET, Mazure CM, Johnston JA, Spencer L, Weathers J, Pittman B, Wang F, Blumberg HP. Brain circuitry associated with the development of substance use in bipolar disorder and preliminary evidence for sexual dimorphism in adolescents. Journal Of Neuroscience Research 2016, 95: 777-791. PMID: 27870392, PMCID: PMC5123602, DOI: 10.1002/jnr.23901.Peer-Reviewed Original ResearchConceptsGray matter volumePrefrontal gray matter volumeBipolar disorderSubstance use problemsFuture substance useSubstance useLower gray matter volumeUse problemsFuture substance use problemsRegional gray matter volumeStructural magnetic resonanceAdverse outcomesTemporopolar cortexInsula gray matter volumeSubstance exposureMood disordersHigh riskLower riskSubsequent alcoholMatter volumeNeurodevelopmental basisSubstance problemsDisordersAdolescentsMales
2013
Cerebral gray matter volumes and low-frequency fluctuation of BOLD signals in cocaine dependence: Duration of use and gender difference
Ide JS, Zhang S, Hu S, Sinha R, Mazure CM, Li CS. Cerebral gray matter volumes and low-frequency fluctuation of BOLD signals in cocaine dependence: Duration of use and gender difference. Drug And Alcohol Dependence 2013, 134: 51-62. PMID: 24090712, PMCID: PMC3865077, DOI: 10.1016/j.drugalcdep.2013.09.004.Peer-Reviewed Original ResearchConceptsGray matter volumeSuperior frontal gyrusDuration of useGM volumeMatter volumeLow-frequency fluctuationsBOLD signalCingulate cortexCD individualsCocaine useCerebral gray matter volumeAlcohol useMiddle/posterior cingulate cortexRight superior frontal gyrusGM volume lossBilateral superior frontal gyrusHealthy control subjectsRight ventral putamenMagnetic resonance imagingChronic cocaine usePosterior cingulate cortexInfluence of ageEffect of ageControl subjectsVentral putamen