2006
Induction of parathyroid hormone‐related peptide following peripheral nerve injury: Role as a modulator of Schwann cell phenotype
Macica CM, Liang G, Lankford KL, Broadus AE. Induction of parathyroid hormone‐related peptide following peripheral nerve injury: Role as a modulator of Schwann cell phenotype. Glia 2006, 53: 637-648. PMID: 16470617, DOI: 10.1002/glia.20319.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornCell DifferentiationCell ProliferationCells, CulturedCyclic AMP Response Element-Binding ProteinDisease Models, AnimalGanglia, SpinalGrowth ConesLigationMiceNerve RegenerationNeurons, AfferentParathyroid Hormone-Related ProteinPeripheral Nerve InjuriesPeripheral NervesRatsRats, Sprague-DawleyReceptor, Parathyroid Hormone, Type 1RNA, MessengerSchwann CellsSciatic NerveSciatic NeuropathyUp-RegulationConceptsSciatic nerve injury modelNerve injury modelPeripheral nerve injuryRole of PTHrPHormone-related peptideSchwann cellsSciatic nerveNerve injuryInjury modelNerve regenerationNervous systemParathyroid hormone-related peptideInjured sciatic nerveDedifferentiated Schwann cellsSchwann cell phenotypeRat nervous systemPeripheral nervous systemPTHrP receptor mRNASuccessful nerve regenerationType 1 collagen matrixSchwann cell culturesSympathetic gangliaPTHrP functionsPTHrP mRNAReceptor mRNA
2005
Stretch‐Induced PTH‐Related Protein Gene Expression in Osteoblasts*
Chen X, Macica CM, Ng KW, Broadus AE. Stretch‐Induced PTH‐Related Protein Gene Expression in Osteoblasts*. Journal Of Bone And Mineral Research 2005, 20: 1454-1461. PMID: 16007342, DOI: 10.1359/jbmr.2005.20.8.1454.Peer-Reviewed Original ResearchConceptsAnabolic effectsStretch-activated potassium channelsCandidate mediatorsCyclical stretchPotassium channelsL-type calcium channelsN-terminal PTHPTHrP mRNA expressionStretch-activated cation channelsSmooth muscle cellsOsteoblast-like cellsUMR 201PTHrP gene expressionHypotonic solutionEndogenous mediatorsPTHrP mRNAIntracellular acidosisExtracellular calciumCalcium channelsFlexercell apparatusPTHrPRNase protection assaysMRNA expressionMuscle cellsSkeletal mass