Endothelin-1 conversion and receptor characterization in human placental arteries
Wilkes B, Macica C, Mento P. Endothelin-1 conversion and receptor characterization in human placental arteries. American Journal Of Physiology 1994, 267: e242-e249. PMID: 8074203, DOI: 10.1152/ajpendo.1994.267.2.e242.Peer-Reviewed Original ResearchConceptsFetoplacental blood vesselsEndothelin-1Big endothelin-1Blood vesselsHuman placental arteriesEndothelin receptor subtypesEndothelin-1 receptorsAtrial natriuretic factorTime-dependent increasePlacental arteriesSpecific receptor sitesPerfusion pressureAngiotensin IIEndothelin receptorsNatriuretic factorReceptor subtypesSmall arteriesPlacental cotyledonsPotency orderFmol/High-affinity binding sitesBig endothelinReceptor characterizationScatchard analysisPressor peptide