2004
Caspase-3 in Postnatal Retinal Development and Degeneration
Zeiss CJ, Neal J, Johnson EA. Caspase-3 in Postnatal Retinal Development and Degeneration. Investigative Ophthalmology & Visual Science 2004, 45: 964-970. PMID: 14985318, DOI: 10.1167/iovs.03-0439.Peer-Reviewed Original ResearchConceptsTerminal dUTP transferase nick end labelingPostnatal retinal developmentCaspase-3Photoreceptor degenerationRod deathMutant miceRetinal developmentInner nuclear layerDouble mutant miceNick end labelingLight microscopic levelRod photoreceptor developmentCell nuclear antigenNeonatal deathRetinal morphometryDysplastic lesionsRetinal dysplasiaNuclear layerPhotoreceptor protectionImmunohistochemical stainingRodent modelsFactor VIICaspase-3 activationNuclear antigenEnd labeling
2003
The Apoptosis-Necrosis Continuum: Insights from Genetically Altered Mice
Zeiss CJ. The Apoptosis-Necrosis Continuum: Insights from Genetically Altered Mice. Veterinary Pathology 2003, 40: 481-495. PMID: 12949404, DOI: 10.1354/vp.40-5-481.Peer-Reviewed Original ResearchConceptsCell death programApoptosis-inducing factorTissue-specific rolesCaspase-dependent mechanismCaspase-dependent apoptosisApoptosis-necrosis continuumAnimal developmentDeath programKey genesApoptotic effectorsApoptotic phenotypeRegulated processCaspase activationIntimate crosstalkApoptotic cascadeDependent effectorsHomeostatic pathwaysCell deathNecrotic onesBiochemical networksApoptosisPathologic stimuliBiochemical featuresMutant miceGenes