Beyond genomics: understanding exposotypes through metabolomics
Rattray NJW, Deziel NC, Wallach JD, Khan SA, Vasiliou V, Ioannidis JPA, Johnson CH. Beyond genomics: understanding exposotypes through metabolomics. Human Genomics 2018, 12: 4. PMID: 29373992, PMCID: PMC5787293, DOI: 10.1186/s40246-018-0134-x.Peer-Reviewed Original ResearchConceptsGene-environment interactionsChallenges of metabolomicsIntegration of genomicsHuman genomeMultiple genetic variantsGenetic variationGenomic technologiesAssociation studiesMetabolic traitsMetabolite productionMetabolic processesIndividual phenotypesMetabolome-wide association studyProtein synthesisHuman population levelGenetic variantsBiological impactGenomicsDisease mechanismsMetabolomic informationWealth of informationPopulation levelSmall moleculesMetabolomicsTraits