Fetal nucleated red blood cells in a rat model of intrauterine growth restriction induced by hypoxia and nitric oxide synthase inhibition
Ravishankar V, Buhimschi CS, Booth CJ, Bhandari V, Norwitz E, Copel J, Buhimschi IA. Fetal nucleated red blood cells in a rat model of intrauterine growth restriction induced by hypoxia and nitric oxide synthase inhibition. American Journal Of Obstetrics And Gynecology 2007, 196: 482.e1-482.e8. PMID: 17466713, DOI: 10.1016/j.ajog.2006.12.020.Peer-Reviewed Original ResearchConceptsIntrauterine growth restrictionNucleated red blood cellsNitric oxide inhibitionFetal nucleated red blood cellsChronic hypoxiaL-NAMEErythropoietin levelsOxide inhibitionRed blood cellsFetal circulationGrowth restrictionFetal bloodHematocrit levelsNumber of NRBCsNitro-L-arginine methyl esterChronic nitric oxide inhibitionMaternal acid-base statusNitric oxide synthase inhibitionBlood cellsMaternal arterial blood gasesOxide synthase inhibitionArterial blood gasesSaline solutionAdult Sprague-DawleyElevated erythropoietin levels