MicroRNAs regulating lipid metabolism in atherogenesis
Rayner K, Fernandez-Hernando C, Moore K. MicroRNAs regulating lipid metabolism in atherogenesis. Thrombosis And Haemostasis 2012, 107: 642-647. PMID: 22274626, PMCID: PMC3618663, DOI: 10.1160/th11-10-0694.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAtherosclerosisATP Binding Cassette Transporter 1ATP-Binding Cassette TransportersCholesterolDisease Models, AnimalFatty AcidsGene Expression RegulationHumansLipid MetabolismLipoproteins, HDLLipoproteins, VLDLLiverMiceMicroRNAsModels, BiologicalSterol Regulatory Element Binding Protein 1Sterol Regulatory Element Binding Protein 2TriglyceridesConceptsSmall non-coding RNAsImportant post-transcriptional regulatorsCellular sterol levelsPost-transcriptional regulatorsNon-coding RNAsVariety of genesSterol response elementFatty acid homeostasisIntronic microRNAsLipid metabolismFatty acid synthesisHost genesTranscription factorsProtein geneCholesterol exportMetabolic programsKey regulatorFatty acid oxidationResponse elementHigh-density lipoproteinMicroRNAsRelated metabolic diseasesGenesABCA1 pathwayAcid homeostasis