2024
Responding to threat: Associations between neural reactivity to and behavioral avoidance of threat in pediatric anxiety
Kitt E, Zacharek S, Odriozola P, Nardini C, Hommel G, Martino A, Anderson T, Spencer H, Broussard A, Dean J, Marin C, Silverman W, Lebowitz E, Gee D. Responding to threat: Associations between neural reactivity to and behavioral avoidance of threat in pediatric anxiety. Journal Of Affective Disorders 2024, 351: 818-826. PMID: 38290579, PMCID: PMC10981528, DOI: 10.1016/j.jad.2024.01.204.Peer-Reviewed Original ResearchConceptsReactivity to threatMeasures of avoidanceVentral anterior insulaClinician-based measuresNeural reactivityPediatric anxietyAnxiety disordersBehavioral avoidanceFunctional magnetic resonance imaging taskAmygdala functional connectivityVentromedial prefrontal cortexTreatment-seeking sampleAvoidance of threatClinically significant constructsAssociated with tasksGeneralizability of findingsPrefrontal cortexAnterior insulaNeural findingsLaboratory tasksFunctional connectivityAnxietyAmygdalaAvoidanceSignificant constructs
2023
Affective Language Spreads Between Anxious Children and Their Mothers During a Challenging Puzzle Task
Nook E, Nardini C, Zacharek S, Hommel G, Spencer H, Martino A, Morra A, Flores S, Anderson T, Marin C, Silverman W, Lebowitz E, Gee D. Affective Language Spreads Between Anxious Children and Their Mothers During a Challenging Puzzle Task. Emotion 2023, 23: 1513-1521. PMID: 36595385, PMCID: PMC10314965, DOI: 10.1037/emo0001203.Peer-Reviewed Original ResearchConceptsNegative affect wordsChallenging puzzle taskAffect wordsAffective languagePuzzle taskEffective emotion regulationSpread of emotionsEmotion regulationNeuroscientific levelAnxious childrenEmotional influencesWord useBidirectional influenceAnxiety disordersBidirectional relationsMother's directionsMental healthEmotionsFuture researchWordsCurrent studyLanguageChildrenTaskMothersMaternal FGF2 levels associated with child anxiety and depression symptoms through child FGF2 levels
Lebowitz E, Marin C, Orbach M, Salmaso N, Vaccarino F, Silverman W. Maternal FGF2 levels associated with child anxiety and depression symptoms through child FGF2 levels. Journal Of Affective Disorders 2023, 326: 193-197. PMID: 36717031, PMCID: PMC10104478, DOI: 10.1016/j.jad.2023.01.090.Peer-Reviewed Original ResearchConceptsFGF2 levelsDepressive symptomsDepression symptomsChild anxietySymptoms of anxietyRatings of anxietyGrowth factor 2Maternal anxietySymptomsDepressed childrenDepressionChild depressionMothersChildrenFactor 2Self-report ratingsAnxietyIntergenerational pathwaysNon-referred childrenRange of anxietyFGF2AssociationLevelsMaternal
2022
Parent Involvement Enhances CBTs for Anxiety Disorders in Hispanic/Latino Youth: Acculturation as a Moderator
Patriarca G, Rey Y, Marin C, Yeguez C, Pettit J, Silverman W. Parent Involvement Enhances CBTs for Anxiety Disorders in Hispanic/Latino Youth: Acculturation as a Moderator. Journal Of Consulting And Clinical Psychology 2022, 90: 827-836. PMID: 36355650, PMCID: PMC9727821, DOI: 10.1037/ccp0000770.Peer-Reviewed Original ResearchConceptsCognitive-behavioral treatmentAnxiety outcomesParent acculturationAnxiety disordersPsychological controlNegative reinforcementEfficacy of CBTParents’ psychological controlYouth anxiety severityHispanic/Latino youthEvidence-based interventionsYouth ages 6Anxiety severityBehavioral treatmentParents' useLatino youthLatino familiesParent involvementAge 6YouthAcculturation levelAcculturationEnculturationModeratorDisordersAttention Training as a Low-Intensity Treatment for Concerning Anxiety in Clinic-Referred Youth
Pettit J, Rey Y, Marin C, Bechor M, Lebowitz E, Vasey M, Jaccard J, Abend R, Pine D, Bar-Haim Y, Silverman W. Attention Training as a Low-Intensity Treatment for Concerning Anxiety in Clinic-Referred Youth. Behavior Therapy 2022, 54: 77-90. PMID: 36608979, PMCID: PMC9825787, DOI: 10.1016/j.beth.2022.07.004.Peer-Reviewed Original ResearchConceptsAttention Bias Modification TreatmentAttention control trainingAttention trainingAnxiety severityAttention controlAnxiety levelsAttention biasNeutral facesLow-intensity treatmentGlobal impairmentDot-probe taskYouth anxiety severityClinic-Referred YouthFull criteriaAttention focusingControl trainingTreatment researchYouthIndependent evaluatorsTrainingImpairment ratingsACT trialsPosttreatmentSeverity ratingsRatingsYouth social functioning interacts with treatment arm, diagnosis, and gender to predict anxiety treatment outcome
Etkin RG, Marin CE, Silverman WK, Lebowitz ER. Youth social functioning interacts with treatment arm, diagnosis, and gender to predict anxiety treatment outcome. Behaviour Research And Therapy 2022, 156: 104160. PMID: 35870327, DOI: 10.1016/j.brat.2022.104160.Peer-Reviewed Original ResearchConceptsAnxiety treatment outcomesYouth social functioningSocial skillsPositive social interactionsSocial functioningAnxiety diagnosesAnxiety disordersSocial interactionParent-based treatmentChildren's social skillsSocial anxiety disorderYouths' social skillsAnxiety symptom severityYouth genderTreatment outcomesDiagnostic InterviewSymptom severityClinical functioningFunctioningSkillsYouthPredictorsMultiple regression modelDisordersGender
2021
Directional effects of parent and child anxiety 1 year following treatment of child anxiety, and the mediational role of parent psychological control
Silverman WK, Marin CE, Rey Y, Jaccard J, Pettit JW. Directional effects of parent and child anxiety 1 year following treatment of child anxiety, and the mediational role of parent psychological control. Depression And Anxiety 2021, 38: 1289-1297. PMID: 34464490, PMCID: PMC8664994, DOI: 10.1002/da.23210.Peer-Reviewed Original ResearchConceptsParents’ psychological controlPsychological controlChild anxietyCognitive behavioral therapyParent anxietyIndividual cognitive behavioral therapyChild's ageAnxiety 1 yearTreatment targetsMediational roleEvidence of childrenBehavioral therapyRecent efficacy trialsParent involvementAnxietyPosttreatmentDirectional effectsParentsClinical implicationsCBT armEvidence of parentChildrenTreatment effectsModeratorEfficacy trialsAttending to the Attentional Control Scale for Children: Confirming its factor structure and measurement invariance
van Son D, Marin CE, Boutris P, Rey Y, Lebowitz ER, Pettit JW, Silverman WK. Attending to the Attentional Control Scale for Children: Confirming its factor structure and measurement invariance. Journal Of Anxiety Disorders 2021, 80: 102399. PMID: 33892347, PMCID: PMC8141040, DOI: 10.1016/j.janxdis.2021.102399.Peer-Reviewed Original ResearchConceptsAttentional Control ScaleTwo-factor modelAttentional controlControl ScaleSelf-report questionnairesTwo-factor structureStrong factorial invarianceConfirmatory factor analysisModel fitAnxious youthAttentional focusingSingle-factor modelFuture research implicationsGood model fitTwo-factorMeasurement invarianceFactorial invariancePartial invarianceFactor structureDiverse sampleConcurrent validityResearch implicationsSubscale scoresPrevious researchFactor analysisFibroblast Growth Factor 2 Implicated in Childhood Anxiety and Depression Symptoms
Lebowitz ER, Orbach M, Marin CE, Salmaso N, Vaccarino FM, Silverman WK. Fibroblast Growth Factor 2 Implicated in Childhood Anxiety and Depression Symptoms. Journal Of Affective Disorders 2021, 282: 611-616. PMID: 33445083, PMCID: PMC7897422, DOI: 10.1016/j.jad.2020.12.055.Peer-Reviewed Original Research
2019
Latino and Non-Latino Parental Treatment Preferences for Child and Adolescent Anxiety Disorders
Seligman LD, Hovey JD, Ibarra M, Hurtado G, Marin CE, Silverman WK. Latino and Non-Latino Parental Treatment Preferences for Child and Adolescent Anxiety Disorders. Child Psychiatry & Human Development 2019, 51: 617-624. PMID: 31807934, DOI: 10.1007/s10578-019-00945-x.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyLatino parentsChild anxietyNon-Latino white parentsAdolescent anxiety disordersParental involvementParental treatment preferencesPerception of burdenMental health treatmentNon-Latino parentsPotential treatment barriersYouth anxietyBehavioral therapyAnxiety disordersChild's treatmentParent involvementTreatment involvementAnxietyHealth treatmentWhite parentsTreatment barriersParents' preferencesGreater preferenceParentsCurrent studyThe Utility of the SCAS-C/P to Detect Specific Anxiety Disorders Among Clinically Anxious Children
Reardon T, Creswell C, Lester KJ, Arendt K, Blatter-Meunier J, Bögels SM, Coleman JRI, Cooper PJ, Heiervang ER, Herren C, Hogendoorn SM, Hudson JL, Keers R, Lyneham HJ, Marin CE, Nauta M, Rapee RM, Roberts S, Schneider S, Silverman WK, Thastum M, Thirlwall K, Wergeland GJ, Eley TC. The Utility of the SCAS-C/P to Detect Specific Anxiety Disorders Among Clinically Anxious Children. Psychological Assessment 2019, 31: 1006-1018. PMID: 31070449, PMCID: PMC6671872, DOI: 10.1037/pas0000700.Peer-Reviewed Original ResearchConceptsSpence Children's Anxiety ScaleSpecific anxiety disordersSocial phobia subscaleSocial anxiety disorderAnxiety disordersFear subscaleQuestionnaire measuresSeparation anxietyGeneralized anxietyAnxiety ScalePreadolescent childrenChildren's Anxiety ScaleClinic-referred sampleSeparation anxiety disorderSeparation anxiety subscaleContribution of childrenFull diagnostic assessmentSCAS subscalesAnxious childrenSocial phobiaChild reportsOptimal cutoff scoreAnxiety subscaleAnxietyCorresponding disorderMeasuring Family Accommodation of Childhood Anxiety: Confirmatory Factor Analysis, Validity, and Reliability of the Parent and Child Family Accommodation Scale – Anxiety
Lebowitz ER, Marin CE, Silverman WK. Measuring Family Accommodation of Childhood Anxiety: Confirmatory Factor Analysis, Validity, and Reliability of the Parent and Child Family Accommodation Scale – Anxiety. Journal Of Clinical Child & Adolescent Psychology 2019, 49: 752-760. PMID: 31136200, PMCID: PMC6881529, DOI: 10.1080/15374416.2019.1614002.Peer-Reviewed Original ResearchConceptsConfirmatory factor analysisFamily accommodationChildhood anxietyExploratory factor analysisTest-retest reliabilityFactor analysisChild anxiety symptomsChild depression symptomsChild-parent dyadsTwo-factor modelTest-retest reliability dataChild anxietyAnxiety symptomsFamily routinesDivergent validityDepression symptomsTest-retest dataConvergent validityFactorial structureKey constructsAnxietyAccommodation measuresTheory developmentClinical applicationStudy objectiveParent-Based Treatment as Efficacious as Cognitive-Behavioral Therapy for Childhood Anxiety: A Randomized Noninferiority Study of Supportive Parenting for Anxious Childhood Emotions
Lebowitz ER, Marin C, Martino A, Shimshoni Y, Silverman WK. Parent-Based Treatment as Efficacious as Cognitive-Behavioral Therapy for Childhood Anxiety: A Randomized Noninferiority Study of Supportive Parenting for Anxious Childhood Emotions. Journal Of The American Academy Of Child & Adolescent Psychiatry 2019, 59: 362-372. PMID: 30851397, PMCID: PMC6732048, DOI: 10.1016/j.jaac.2019.02.014.Peer-Reviewed Original ResearchConceptsParent-based treatmentAnxious Childhood EmotionsChildhood anxiety disordersFamily accommodationChildhood anxietyAnxiety disordersChildhood EmotionsSupportive parentingParenting stressAnxiety outcomesCognitive behavioral therapyPrimary anxiety disorderParent interventionBehavioral therapyChildren's ratingsAnxiety severityTreatment credibilityClinician-rated scalesParent treatmentParent involvementAnxietyDiagnostic InterviewEmotionsParentingIndependent evaluators
2017
Social Media Use, Friendship Quality, and the Moderating Role of Anxiety in Adolescents with Autism Spectrum Disorder
van Schalkwyk GI, Marin CE, Ortiz M, Rolison M, Qayyum Z, McPartland JC, Lebowitz ER, Volkmar FR, Silverman WK. Social Media Use, Friendship Quality, and the Moderating Role of Anxiety in Adolescents with Autism Spectrum Disorder. Journal Of Autism And Developmental Disorders 2017, 47: 2805-2813. PMID: 28616856, PMCID: PMC6688174, DOI: 10.1007/s10803-017-3201-6.Peer-Reviewed Original ResearchConceptsFriendship qualityAnxiety levelsSocial media useHigher friendship qualityComplex social informationAutism spectrum disorderMedia useSpectrum disorderSocial informationModerating RoleSocial mediaSocial engagementASDOffline social activitiesAnxietyAdolescentsSignificant anxietyComparison controlsSocial activities
2016
Genome-wide association study of response to cognitive–behavioural therapy in children with anxiety disorders
Coleman JR, Lester KJ, Keers R, Roberts S, Curtis C, Arendt K, Bögels S, Cooper P, Creswell C, Dalgleish T, Hartman CA, Heiervang ER, Hötzel K, Hudson JL, In-Albon T, Lavallee K, Lyneham HJ, Marin CE, Meiser-Stedman R, Morris T, Nauta MH, Rapee RM, Schneider S, Schneider SC, Silverman WK, Thastum M, Thirlwall K, Waite P, Wergeland GJ, Breen G, Eley TC. Genome-wide association study of response to cognitive–behavioural therapy in children with anxiety disorders. The British Journal Of Psychiatry 2016, 209: 236-243. PMID: 26989097, PMCID: PMC5007453, DOI: 10.1192/bjp.bp.115.168229.Peer-Reviewed Original Research
2015
Predictors of treatment outcome in an effectiveness trial of cognitive behavioral therapy for children with anxiety disorders
Wergeland GJ, Fjermestad KW, Marin CE, Bjelland I, Haugland BS, Silverman WK, Öst LG, Bjaastad JF, Oeding K, Havik OE, Heiervang ER. Predictors of treatment outcome in an effectiveness trial of cognitive behavioral therapy for children with anxiety disorders. Behaviour Research And Therapy 2015, 76: 1-12. PMID: 26583954, DOI: 10.1016/j.brat.2015.11.001.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyChild-rated anxiety symptomsParent internalizing symptomsAnxiety disordersAnxiety symptomsCBT programInternalizing symptomsSocial phobiaBehavioral therapyLower family social classPrimary anxiety disorderSeparation anxiety disorderPositive treatment outcomesFamily social classChildren of parentsAnxious childrenEffectiveness trialChildren's motivationParent factorsSeparation anxietyTreatment outcomesSymptom levelsRecent effectiveness studiesPoor outcomePhobiaMoving to Second-Stage Treatments Faster: Identifying Midtreatment Tailoring Variables for Youth with Anxiety Disorders
Pettit JW, Silverman WK, Rey Y, Marin C, Jaccard J. Moving to Second-Stage Treatments Faster: Identifying Midtreatment Tailoring Variables for Youth with Anxiety Disorders. Journal Of Clinical Child & Adolescent Psychology 2015, 45: 457-468. PMID: 25984794, PMCID: PMC4651669, DOI: 10.1080/15374416.2015.1038824.Peer-Reviewed Original ResearchClinical Predictors of Response to Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders: The Genes for Treatment (GxT) Study
Hudson JL, Keers R, Roberts S, Coleman JR, Breen G, Arendt K, Bögels S, Cooper P, Creswell C, Hartman C, Heiervang ER, Hötzel K, In-Albon T, Lavallee K, Lyneham HJ, Marin CE, McKinnon A, Meiser-Stedman R, Morris T, Nauta M, Rapee RM, Schneider S, Schneider SC, Silverman WK, Thastum M, Thirlwall K, Waite P, Wergeland GJ, Lester KJ, Eley TC. Clinical Predictors of Response to Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders: The Genes for Treatment (GxT) Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 2015, 54: 454-463. PMID: 26004660, PMCID: PMC4469376, DOI: 10.1016/j.jaac.2015.03.018.Peer-Reviewed Original ResearchPredictors of dropout from community clinic child CBT for anxiety disorders
Wergeland GJ, Fjermestad KW, Marin CE, Haugland BS, Silverman WK, Öst LG, Havik OE, Heiervang ER. Predictors of dropout from community clinic child CBT for anxiety disorders. Journal Of Anxiety Disorders 2015, 31: 1-10. PMID: 25637909, DOI: 10.1016/j.janxdis.2015.01.004.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAmbulatory CareAnxiety DisordersAttitude to HealthChildCognitive Behavioral TherapyCommunity Mental Health CentersFemaleHumansInternal-External ControlMaleMotivationParentsPatient DropoutsPsychiatric Status Rating ScalesPsychotherapy, GroupSelf ConceptSurveys and QuestionnairesConceptsCognitive behavior therapyTreatment credibilityOverall dropoutsAnxiety disordersLate dropoutGroup cognitive behavior therapyInternalizing symptomsPredictors of dropoutCommunity clinicsEffectiveness trialTreatment dropoutLower childSymptomsBehavior therapyEarly dropoutSignificant differencesChildrenPredictorsDisordersDropout rateClinicTherapyParentsDropoutTrialsFamily accommodation mediates the association between anxiety symptoms in mothers and children
Jones JD, Lebowitz ER, Marin CE, Stark KD. Family accommodation mediates the association between anxiety symptoms in mothers and children. Journal Of Child And Adolescent Mental Health 2015, 27: 41-51. PMID: 25958796, DOI: 10.2989/17280583.2015.1007866.Peer-Reviewed Original ResearchConceptsFamily accommodationChild anxietyStructural equation modellingAnxiety symptomsMaternal anxietySubclinical anxiety symptomsPediatric anxiety disordersDevelopment of interventionsChild avoidMothers of childrenMediational roleGreater symptom severityAnxiety disordersOwn anxietyMaternal accommodationAnxietyEquation modellingPoor treatment outcomesSymptom severityParentsChildrenTreatment outcomesAccommodationYouthMothers