2023
Evidence Accumulates: Patients with Ascending Aneurysms Are Strongly Protected from Atherosclerotic Disease
Waldron C, Zafar M, Ziganshin B, Weininger G, Grewal N, Elefteriades J. Evidence Accumulates: Patients with Ascending Aneurysms Are Strongly Protected from Atherosclerotic Disease. International Journal Of Molecular Sciences 2023, 24: 15640. PMID: 37958625, PMCID: PMC10650782, DOI: 10.3390/ijms242115640.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAortic aneurysmCarotid intima-media thicknessLow-density lipoprotein levelsIntima-media thicknessDevelopment of atherosclerosisMatrix metalloproteinase proteinsAscending aneurysmAortic calcificationAtherosclerotic diseaseLipoprotein levelsMyocardial infarctionLeading causeAneurysmsMetalloproteinase proteinsGrowth factorProtective relationshipDiseasePossible mechanismCurrent understandingMorbidityInfarctionAtherosclerosisPatientsPathophysiology
2014
Surgical management of thoracoabdominal aneurysms
Ziganshin BA, Elefteriades JA. Surgical management of thoracoabdominal aneurysms. Heart 2014, 100: 1577. PMID: 25092876, DOI: 10.1136/heartjnl-2013-305131.Peer-Reviewed Original ResearchMeSH KeywordsAortic Aneurysm, ThoracicHumansPractice Guidelines as TopicTreatment OutcomeVascular Surgical ProceduresConceptsThoracoabdominal aneurysmsSurgical managementApplication of hypothermiaCerebrospinal fluid drainageType of treatmentParaplegia ratePostoperative mortalityHospital stayComplication rateSurgical treatmentHeart bypassHybrid repairTreatment adjunctsMorbid conditionsFluid drainageHigh mortalityTAAASignificant decreaseAneurysmsTreatmentMortalityNeuromonitoringPatientsStayAortaStraight deep hypothermic circulatory arrest for cerebral protection during aortic arch surgery: Safe and effective
Ziganshin BA, Rajbanshi BG, Tranquilli M, Fang H, Rizzo JA, Elefteriades JA. Straight deep hypothermic circulatory arrest for cerebral protection during aortic arch surgery: Safe and effective. Journal Of Thoracic And Cardiovascular Surgery 2014, 148: 888-900. PMID: 25052822, DOI: 10.1016/j.jtcvs.2014.05.027.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAorta, ThoracicAortic Aneurysm, ThoracicAortic DissectionCerebrovascular CirculationChi-Square DistributionCirculatory Arrest, Deep Hypothermia InducedFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioOperative TimePostoperative ComplicationsRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeVascular Surgical ProceduresYoung AdultConceptsDeep hypothermic circulatory arrestMinutes of DHCAStraight deep hypothermic circulatory arrestAortic arch surgeryHypothermic circulatory arrestCerebral protectionStroke rateArch surgeryCirculatory arrestAortic archPostoperative stroke rateSignificant postoperative mortalityComposite adverse outcomeOverall stroke rateExtensive clinical experienceDHCA durationElective mortalityPostoperative mortalityNeurologic sequelaeExperienced centersRenal failureAortic dissectionConsecutive patientsOverall mortalityDHCA time