2012
Psoriasis and Down syndrome: a report of three cases and a potential pathophysiologic link.
Marmon S, De Souza A, Strober B. Psoriasis and Down syndrome: a report of three cases and a potential pathophysiologic link. Dermatology Online Journal 2012, 18: 13. PMID: 22747937, DOI: 10.5070/d305m5f4bx.Peer-Reviewed Original ResearchConceptsDown syndromeSerum levelsIFN-gammaChronic plaque psoriasisPotential pathophysiologic linksHigher serum levelsCases of patientsProduction of cytokinesTumor necrosis factorTh1 lineage cellsPathophysiologic linkPlaque psoriasisTh17 cellsTh17 pathwayPatient populationIL-2Healthy controlsNecrosis factorGreater prevalencePsoriasisSyndromeIFN systemPatientsLineage cellsCells
2011
SAPHO syndrome associated with hidradenitis suppurativa successfully treated with infliximab and methotrexate.
De Souza A, Solomon G, Strober B. SAPHO syndrome associated with hidradenitis suppurativa successfully treated with infliximab and methotrexate. Bulletin Of The NYU Hospital For Joint Disease 2011, 69: 185-7. PMID: 22035400.Peer-Reviewed Original ResearchConceptsHidradenitis suppurativaInflammatory musculoskeletal disordersPrevious ineffective treatmentRefractory SAPHO syndromeSafety of infliximabOral antibioticsComplete remissionSAPHO syndromeFirst doseCutaneous featuresContinued treatmentUnknown etiologyCase reportAcne vulgarisMusculoskeletal disordersIneffective treatmentInfliximabSkin abnormalitiesSyndromeYoung adultsSuppurativaJoint stiffnessTreatmentRemissionArthritis