2016
Treatment of Moderate to Severe Pediatric Psoriasis: A Retrospective Case Series
Klufas D, Wald J, Strober B. Treatment of Moderate to Severe Pediatric Psoriasis: A Retrospective Case Series. Pediatric Dermatology 2016, 33: 142-149. PMID: 26871417, DOI: 10.1111/pde.12782.Peer-Reviewed Original ResearchConceptsSevere pediatric psoriasisRetrospective case seriesPediatric psoriasisCase seriesSevere psoriasisSystemic therapySide effectsDisease responseSimilar side effect profilePhysician Global Assessment scaleComprehensive safety profileSmall sample sizeSingle referral centerSubjective side effectsSide effect profileSafety of treatmentMultiple treatment optionsAdverse event occurrenceComparison of efficacyGlobal Assessment ScalePaucity of dataAdult psoriasisImmunomodulating therapiesAdverse eventsReferral center
2006
Comparison of Tazarotene and Minocycline Maintenance Therapies in Acne Vulgaris: A Multicenter, Double-blind, Randomized, Parallel-Group Study
Leyden J, Thiboutot D, Shalita A, Webster G, Washenik K, Strober B, Shupack J. Comparison of Tazarotene and Minocycline Maintenance Therapies in Acne Vulgaris: A Multicenter, Double-blind, Randomized, Parallel-Group Study. JAMA Dermatology 2006, 142: 605-612. PMID: 16702498, DOI: 10.1001/archderm.142.5.605.Peer-Reviewed Original ResearchConceptsGreater global improvementMaintenance therapyTazarotene gelGlobal improvementLesion countsAcne vulgarisOpen-label treatment phaseParallel-group studyInflammatory lesion countSevere acne vulgarisOverall disease severityPlacebo capsulesMaintenance regimensReferral centerWeek 24Severe acneVehicle gelAmbulatory patientsWeek 12Minocycline therapyAntibiotic exposureMean reductionTreatment phasePatientsGreater efficacy