2013
Community differentiation of the cutaneous microbiota in psoriasis
Alekseyenko A, Perez-Perez G, De Souza A, Strober B, Gao Z, Bihan M, Li K, Methé B, Blaser M. Community differentiation of the cutaneous microbiota in psoriasis. Microbiome 2013, 1: 31. PMID: 24451201, PMCID: PMC4177411, DOI: 10.1186/2049-2618-1-31.Peer-Reviewed Original ResearchCutaneous microbiotaLesion specimensCommon chronic inflammatory diseaseSkin typeChronic inflammatory diseasePsoriasis patientsPsoriatic patientsContralateral skinDifferential microbiotaInflammatory diseasesSkin colonizationHealthy controlsPsoriatic lesionsLesion siteDiagnostic significanceLesion samplesClinical diagnosisPsoriasis samplesPsoriasisSystemic levelsUseful predictorConclusionsOur resultsMicrobiotaPatientsLesions
2008
Substantial Alterations of the Cutaneous Bacterial Biota in Psoriatic Lesions
Gao Z, Tseng C, Strober B, Pei Z, Blaser M. Substantial Alterations of the Cutaneous Bacterial Biota in Psoriatic Lesions. PLOS ONE 2008, 3: e2719. PMID: 18648509, PMCID: PMC2447873, DOI: 10.1371/journal.pone.0002719.Peer-Reviewed Original ResearchConceptsPsoriatic lesionsHealthy personsIdiopathic inflammatory disorderNormal skin samplesBroad-range PCRPsoriatic patientsInflammatory disordersUninvolved skinPsoriatic skinCutaneous samplesNormal skinPatientsLesion samplesNormal personsSubstantial alterationsLesionsPropionibacterium speciesSkin samplesPsoriasisSkinSpecies-level operational taxonomic unitsRDNA PCRAlterationsExtracted DNARange PCR
2006
Molecular Analysis of Fungal Microbiota in Samples from Healthy Human Skin and Psoriatic Lesions
Paulino L, Tseng C, Strober B, Blaser M. Molecular Analysis of Fungal Microbiota in Samples from Healthy Human Skin and Psoriatic Lesions. Journal Of Clinical Microbiology 2006, 44: 2933-2941. PMID: 16891514, PMCID: PMC1594634, DOI: 10.1128/jcm.00785-06.Peer-Reviewed Original ResearchConceptsRibosomal DNAHost-specific variationPsoriatic lesionsHealthy skinHealthy human skinRDNA/Unknown phylotypesFungal communitiesITS2 analysisMost organismsNew speciesSpecies distributionFungal microbiotaPCR primersHuman skinMolecular analysisCommon cutaneous diseasesPCR analysisUnknown etiologyCutaneous diseaseHealthy subjectsPsoriatic skinOrganismsSpeciesMicrobiota composition