Psoriasis and Down syndrome: a report of three cases and a potential pathophysiologic link.
Marmon S, De Souza A, Strober B. Psoriasis and Down syndrome: a report of three cases and a potential pathophysiologic link. Dermatology Online Journal 2012, 18: 13. PMID: 22747937, DOI: 10.5070/d305m5f4bx.Peer-Reviewed Original ResearchConceptsDown syndromeSerum levelsIFN-gammaChronic plaque psoriasisPotential pathophysiologic linksHigher serum levelsCases of patientsProduction of cytokinesTumor necrosis factorTh1 lineage cellsPathophysiologic linkPlaque psoriasisTh17 cellsTh17 pathwayPatient populationIL-2Healthy controlsNecrosis factorGreater prevalencePsoriasisSyndromeIFN systemPatientsLineage cellsCells