2013
Effect of tofacitinib, a Janus kinase inhibitor, on haematological parameters during 12 weeks of psoriasis treatment
Strober B, Buonanno M, Clark J, Kawabata T, Tan H, Wolk R, Valdez H, Langley R, Harness J, Menter A, Papp K. Effect of tofacitinib, a Janus kinase inhibitor, on haematological parameters during 12 weeks of psoriasis treatment. British Journal Of Dermatology 2013, 169: 992-999. PMID: 23855761, DOI: 10.1111/bjd.12517.Peer-Reviewed Original ResearchConceptsPhase IIb trialJanus kinase inhibitorDose-dependent decreaseTofacitinib 2IIb trialCell countNatural killer cell countsReversible dose-dependent decreaseSevere chronic plaque psoriasisHaematological parametersKinase inhibitorsB-cell countsChronic plaque psoriasisEffects of tofacitinibShort-term administrationClear dose-dependent effectTreatment of psoriasisRed blood cell countBlood cell countWhite blood cellsDose-dependent effectDose-dependent changesHaematology dataPlaque psoriasisLymphocyte count
2007
From the Medical Board of the National Psoriasis Foundation: Monitoring and vaccinations in patients treated with biologics for psoriasis
Lebwohl M, Bagel J, Gelfand J, Gladman D, Gordon K, Hsu S, Kalb R, Kimball A, Korman N, Krueger G, Mease P, Morison W, Paller A, Pariser D, Ritchlin C, Strober B, Van Voorhees A, Weinstein G, Young M, Horn L. From the Medical Board of the National Psoriasis Foundation: Monitoring and vaccinations in patients treated with biologics for psoriasis. Journal Of The American Academy Of Dermatology 2007, 58: 94-105. PMID: 17980456, DOI: 10.1016/j.jaad.2007.08.030.Peer-Reviewed Original ResearchConceptsLiver function testsBiologic therapyNational Psoriasis FoundationCD4 countAntinuclear antibodiesFunction testsPlatelet countPhysical examinationVaccination practicesTumor necrosis factor blockersNecrosis factor blockersTuberculin skin testTreatment of psoriasisBlood cell countEvidence-based studiesMedical boardsFactor blockersPsoriatic arthritisSkin testBlood countConsensus conferenceParticular therapyBlood chemistryPatientsLive vaccine