2013
Emotion self-regulation and empathy depend upon longer stimulus exposure
Ikezawa S, Corbera S, Wexler BE. Emotion self-regulation and empathy depend upon longer stimulus exposure. Social Cognitive And Affective Neuroscience 2013, 9: 1561-1568. PMID: 24064924, PMCID: PMC4187273, DOI: 10.1093/scan/nst148.Peer-Reviewed Original ResearchConceptsLate positive potentialSelf-regulatory processesEvent-related potentialsEmpathic responsesLate event-related potentialsThreat-related stimuliPain-related stimuliLonger stimulus exposuresLate ERP componentsPictures of handsStimulus exposure durationAttentional modulationERP responsesERP componentsNeural basisBrain processingStimulus exposureTask conditionsStimulus presentationNeutral situationsProcessing existClinical populationsStimulus durationExposure durationJudgment condition
2012
Computerized cognitive remediation training for schizophrenia: An open label, multi-site, multinational methodology study
Murthy NV, Mahncke H, Wexler BE, Maruff P, Inamdar A, Zucchetto M, Lund J, Shabbir S, Shergill S, Keshavan M, Kapur S, Laruelle M, Alexander R. Computerized cognitive remediation training for schizophrenia: An open label, multi-site, multinational methodology study. Schizophrenia Research 2012, 139: 87-91. PMID: 22342330, DOI: 10.1016/j.schres.2012.01.042.Peer-Reviewed Original ResearchConceptsFunctional capacity outcome measuresCognitive Assessment InterviewBrain Fitness ProgramSignificant treatment effectOutcome measuresRegular antipsychotic medicationStable adult patientsNon-pharmacological methodsCognitive performanceTreatment effectsComputerized cognitive remediation trainingMultinational clinical trialsSingle-site studyTraining effectsCognitive remediation trainingOpen labelAdult patientsAntipsychotic medicationCAI scoreClinical trialsCognitive impairmentMulti-site studyExercise taskRemediation trainingNeuropsychological tasks
2007
Neurocognitive enhancement therapy with work therapy in schizophrenia: 6-month follow-up of neuropsychological performance
Bell M, Fiszdon J, Greig T, Wexler B, Bryson G. Neurocognitive enhancement therapy with work therapy in schizophrenia: 6-month follow-up of neuropsychological performance. The Journal Of Rehabilitation Research And Development 2007, 44: 761. PMID: 17943687, DOI: 10.1682/jrrd.2007.02.0032.Peer-Reviewed Original ResearchConceptsNeurocognitive enhancement therapyWork therapyEnhancement therapyExecutive function tasksComputer-based trainingNonverbal memoryFunction tasksExecutive functionNeuropsychological performanceNeuropsychological testsNeuropsychological assessmentCognitive deficitsCompletion of trainingNeuropsychological improvementOccupational dysfunctionMemorySchizoaffective disorderCurrent studySchizophreniaTrainingJob placementWork activitiesActive interventionTaskAnalysis of variance
2005
Neurocognitive enhancement therapy with work therapy: Productivity outcomes at 6- and 12-month follow-ups
Bell MD, Bryson GJ, Greig TC, Fiszdon JM, Wexler BE. Neurocognitive enhancement therapy with work therapy: Productivity outcomes at 6- and 12-month follow-ups. The Journal Of Rehabilitation Research And Development 2005, 42: 829. PMID: 16680620, DOI: 10.1682/jrrd.2005.03.0061.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognitive Behavioral TherapyCombined Modality TherapyFollow-Up StudiesHumansMiddle AgedNeuropsychological TestsOdds RatioPatient ComplianceProbabilityPsychiatric Status Rating ScalesPsychotic DisordersRehabilitation, VocationalRisk AssessmentSchizophreniaTask Performance and AnalysisTime FactorsTreatment OutcomeConceptsNeurocognitive enhancement therapyWork therapyCognitive trainingEnhancement therapyComputerized cognitive trainingExecutive functionWork outcomesCommunity mental health centerDiagnosis of schizophreniaMental health centersMental hygiene clinicSchizoaffective disorderRandom effects analysisNet trainingProductivity outcomesTrainingRehabilitation programSchizophreniaMore hoursMemoryPresent studyDisordersOutcomesEffect analysisFindings
2004
Functional MRI changes before and after onset of reported emotions
Prohovnik I, Skudlarski P, Fulbright RK, Gore JC, Wexler BE. Functional MRI changes before and after onset of reported emotions. Psychiatry Research 2004, 132: 239-250. PMID: 15664795, DOI: 10.1016/j.pscychresns.2004.03.005.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingEmotional responsesConscious emotional experienceBrain regionsBrain-imaging studiesSubjective emotional responsesNegative emotional responsesFace social interactionsSuperior temporal gyrusMiddle frontal gyrusEmotion-related behaviorsDistinctive brain regionsMultiple brain regionsCognitive tasksEvoked emotionHealthy young adultsNeural correlatesSad conditionEmotional experienceFrontal gyrusReported onsetEmotional stimulationTemporal gyrusSensory regionsSocial interactionDurability of cognitive remediation training in schizophrenia: performance on two memory tasks at 6-month and 12-month follow-up
Fiszdon JM, Bryson GJ, Wexler BE, Bell MD. Durability of cognitive remediation training in schizophrenia: performance on two memory tasks at 6-month and 12-month follow-up. Psychiatry Research 2004, 125: 1-7. PMID: 14967547, DOI: 10.1016/j.psychres.2003.10.004.Peer-Reviewed Original ResearchConceptsCognitive remediation trainingSerial position taskComputerized cognitive remediationDigit span taskSpan taskRemediation trainingCognitive remediationMemory taskPosition taskComputerized cognitive remediation trainingWork therapyActive control conditionGroups of participantsSignificant group differencesComputerized trainingCognitive retrainingComputerized tasksTraining tasksCognitive improvementCognitive deficitsCompletion of trainingGroup differencesControl conditionTaskTraining