2004
Durability of cognitive remediation training in schizophrenia: performance on two memory tasks at 6-month and 12-month follow-up
Fiszdon JM, Bryson GJ, Wexler BE, Bell MD. Durability of cognitive remediation training in schizophrenia: performance on two memory tasks at 6-month and 12-month follow-up. Psychiatry Research 2004, 125: 1-7. PMID: 14967547, DOI: 10.1016/j.psychres.2003.10.004.Peer-Reviewed Original ResearchConceptsCognitive remediation trainingSerial position taskComputerized cognitive remediationDigit span taskSpan taskRemediation trainingCognitive remediationMemory taskPosition taskComputerized cognitive remediation trainingWork therapyActive control conditionGroups of participantsSignificant group differencesComputerized trainingCognitive retrainingComputerized tasksTraining tasksCognitive improvementCognitive deficitsCompletion of trainingGroup differencesControl conditionTaskTraining
2002
Deficits in language-mediated mental operations in patients with schizophrenia
Wexler BE, Donegan N, Stevens AA, Jacob SA. Deficits in language-mediated mental operations in patients with schizophrenia. Schizophrenia Research 2002, 53: 171-179. PMID: 11738530, DOI: 10.1016/s0920-9964(01)00194-3.Peer-Reviewed Original ResearchConceptsMemory taskMemory deficitsMemory testFamiliar soundsNon-verbal memory testsEarly perceptual processingSerial position taskWord memory taskVerbal memory processesVerbal memory taskNon-verbal memoryVerbal memory testsPerceptual processingAttentional competenceVerbal materialVerbal stimuliStimulus itemsMemory processesMental operationsTask difficultyVisual stimuliImpaired performancePosition taskSensory processingAuditory tests
2000
Verbal Processing Deficits in Schizophrenia
Stevens A, Donegan N, Anderson M, Goldman-Rakic P, Wexler B. Verbal Processing Deficits in Schizophrenia. Journal Of Psychopathology And Clinical Science 2000, 109: 461-471. PMID: 11016116, DOI: 10.1037/0021-843x.109.3.461.Peer-Reviewed Original ResearchConceptsSerial position taskPosition taskVerbal tasksLanguage-related processingNonword stimuliProactive interferenceWord taskProcessing deficitsVerbal deficitsSpecific deficitsVisual presentationTaskDeficitsStimuliDifferential effectsSchizophrenic patientsDifferent testsToneSchizophreniaProcessingFindings
1998
Word and Tone Working Memory Deficits in Schizophrenia
Wexler BE, Stevens AA, Bowers AA, Sernyak MJ, Goldman-Rakic PS. Word and Tone Working Memory Deficits in Schizophrenia. JAMA Psychiatry 1998, 55: 1093-1096. PMID: 9862552, DOI: 10.1001/archpsyc.55.12.1093.Peer-Reviewed Original ResearchConceptsMemory testNonverbal testsVerbal testsMemory deficitsSerial position taskTests of perceptionAuditory memory testVerbal memory deficitsWorking Memory DeficitsImmediate recall taskSignificant performance deficitsRecall taskVerbal memoryPerceptual functionsSustained attentionDiscrimination taskPitch discriminationSelective deficitNormal motivationPerformance deficitsPosition taskMemory testingCognitive functionMedicated outpatientsInformation processingCortical Dysfunction in Schizophrenia During Auditory Word and Tone Working Memory Demonstrated by Functional Magnetic Resonance Imaging
Stevens AA, Goldman-Rakic PS, Gore JC, Fulbright RK, Wexler BE. Cortical Dysfunction in Schizophrenia During Auditory Word and Tone Working Memory Demonstrated by Functional Magnetic Resonance Imaging. JAMA Psychiatry 1998, 55: 1097-1103. PMID: 9862553, DOI: 10.1001/archpsyc.55.12.1097.Peer-Reviewed Original ResearchConceptsSerial position taskFunctional magnetic resonance imagingInferior frontal gyrusPosition taskMemory deficitsFrontal gyrusLeft inferior frontal gyrusAnterior temporal lobe areasTask-specific activationFunctional magnetic resonanceSpeech-related areasCortical hemodynamic responsesTemporal lobe areasSevere cognitive deficitsAuditory wordsWorking memoryVerbal learningNeural basisSuch deficitsCognitive deficitsCognitive functionParietal lobeLobe areasMagnetic resonance imagingCognitive dysfunction