1992
Pharmacology of agents used in bone marrow transplant conditioning regimens
Wiebe V, Smith B, DeGregorio M, Rappeport J. Pharmacology of agents used in bone marrow transplant conditioning regimens. Critical Reviews In Oncology/Hematology 1992, 13: 241-270. PMID: 1476655, DOI: 10.1016/1040-8428(92)90092-5.Peer-Reviewed Original ResearchConceptsBone marrow transplantationTotal body irradiationConditioning regimensPharmacology of agentsSingle fraction total body irradiationTransplant conditioning regimensTransplantation conditioning regimensConditioning regimentEffective immunosuppressionTBI regimensBody irradiationMarrow transplantationCurative potentialEngraftment rateDonor histocompatibilityToxicity profilePharmacologic behaviorRegimensAntineoplastic propertiesHematopoietic spaceAntineoplastic activityDisease statesPharmacology
1985
Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria: eradication of the PNH clone and documentation of complete lymphohematopoietic engraftment.
Antin JH, Ginsburg D, Smith BR, Nathan DG, Orkin SH, Rappeport JM. Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria: eradication of the PNH clone and documentation of complete lymphohematopoietic engraftment. Blood 1985, 66: 1247-50. PMID: 3904867, DOI: 10.1182/blood.v66.6.1247.bloodjournal6661247.Peer-Reviewed Original ResearchConceptsParoxysmal nocturnal hemoglobinuriaBone marrow transplantationConditioning regimenMarrow transplantationMarrow aplasiaPNH cloneNocturnal hemoglobinuriaPretransplant conditioning regimenCurative therapyAntithymocyte serumComplete engraftmentMarrow graftingSuccessful treatmentAbnormal clonePatientsHematopoietic stem cellsRBC typingTransplantationRegimenCell linesAplasiaDNA sequence polymorphism analysisEngraftmentHemoglobinuriaStem cells
1984
Busulfan and total body irradiation as antihematopoietic stem cell agents in the preparation of patients with congenital bone marrow disorders for allogenic bone marrow transplantation.
Parkman R, Rappeport JM, Hellman S, Lipton J, Smith B, Geha R, Nathan DG. Busulfan and total body irradiation as antihematopoietic stem cell agents in the preparation of patients with congenital bone marrow disorders for allogenic bone marrow transplantation. Blood 1984, 64: 852-7. PMID: 6383499, DOI: 10.1182/blood.v64.4.852.bloodjournal644852.Peer-Reviewed Original ResearchConceptsTotal body irradiationBone marrow transplantationBone marrow disordersBody irradiationPreparation of patientsMarrow transplantationMarrow disordersInterstitial pneumonitisAllogeneic bone marrow transplantationAllogenic bone marrow transplantationIdiopathic interstitial pneumonitisCell agentsPreparatory regimenBusulfanPatientsHematopoietic stem cellsTransplantationTransplantPneumonitisDisordersHematopoietic ablationStem cellsRegimenRegimensAgents